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Home › Research › Clinical trials

Clinical trials

Every Alzheimer's trial in our copy of the ClinicalTrials.gov registry — completed, running and abandoned. Filter it, then follow the link to the official record.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

Clear filters Download all 7,816 as CSV

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 7,776–7,800 of 7,816 matching trials · page 312 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
A Study of the Safety and Efficacy of Multiple Doses of ABT-089 in Subjects With Alzheimer's Disease
NCT00069849
ABT-089
Runs in: United States · 8 sites 		PHASE2
other		 TERMINATED 64 Abbott
INDUSTRY		 2006-09-04
Study of Escitalopram Versus Placebo in the Treatment of Depressive Syndrome in Alzheimer's Disease, Vascular Dementia, and Mixed Vascular and Alzheimer's Dementia
NCT00229333
Escitalopram
Runs in: Israel · 1 site 		PHASE4
other		 UNKNOWN 40 Sheba Medical Center
OTHER_GOV		 2006-08-29
Preventing Cognitive Decline With Alternative Therapies
NCT00010920
Ginkgo Biloba Extract
Runs in: United States · 1 site 		PHASE3
other		 COMPLETED — National Center for Complementary and Integrative Health (NCCIH)
NIH		 2006-08-18
Creatine Therapy for Huntington's Disease
NCT00026988
Creatine
Runs in: United States · 4 sites 		PHASE1|PHASE2
other		 COMPLETED 64 National Center for Complementary and Integrative Health (NCCIH)
NIH		 2006-08-18
Study of Depakote for Behavioral and Psychological Symptoms in Dementia
NCT00197834
Depakote
Runs in: United States · 1 site 		PHASE1
other		 UNKNOWN 20 Hearthstone Alzheimer Care
INDUSTRY		 2006-08-15
Guanfacine to Treat Borderline Personality Disorder
NCT00358969
guanfacine (Tenex)
Runs in: United States · 1 site 		NA
other		 UNKNOWN — Icahn School of Medicine at Mount Sinai
OTHER		 2006-08-01
Care Management for Patients With Alzheimer Disease and Their Family Caregivers
NCT00246896
care management
Runs in: United States · 1 site 		NA
other		 COMPLETED 220 Agency for Healthcare Research and Quality (AHRQ)
OTHER_GOV		 2006-07-27
High Intensity Light Therapy in Alzheimer's Disease
NCT00065689
high-intensity light therapy
Runs in: United States · 1 site 		PHASE3
other		 COMPLETED 107 National Center for Complementary and Integrative Health (NCCIH)
NIH		 2006-07-26
Efficacy and Safety of LY451395 in Patients With Probable Alzheimer's Disease
NCT00051909
LY451395
Runs in: United States · 9 sites 		PHASE2
other		 COMPLETED 200 Eli Lilly and Company
INDUSTRY		 2006-07-19
Multidisciplinary Inpatient Palliative Care Intervention
NCT00325611
Multidisciplinary palliative care team met with patient
Runs in: United States · 1 site 		NA
other		 COMPLETED 550 Kaiser Permanente
OTHER		 2006-05-15
Computer-Based Therapy for Mild Cognitive Impairment
NCT00319943
Computer-based training for Mild Cognitive Impairment (MCI)
Runs in: United States · 1 site 		PHASE1
other		 COMPLETED 48 Posit Science Corporation
INDUSTRY		 2006-04-27
Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects
NCT00000362
Chin-down position; Thickened liquid administration
Runs in: United States · 1 site 		PHASE3
other		 TERMINATED 600 National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH		 2006-04-24
TNF-Alpha Inhibition for Treatment of Alzheimer's Disease
NCT00203320
etanercept given by perispinal administration
Runs in: United States · 1 site 		PHASE1
other		 COMPLETED 30 Tobinick, Edward Lewis, M.D.
OTHER		 2006-04-24
TNF-Alpha Inhibition for Treatment of Alzheimer's Disease
NCT00203359
etanercept given by perispinal administration
Runs in: United States · 1 site 		PHASE1
other		 COMPLETED 15 Tobinick, Edward Lewis, M.D.
OTHER		 2006-04-24
Risperidone Alone Vs. Risperidone Plus Valproate in the Treatment of Patients With Schizophrenia and Hostility
NCT00308360
Risperidone, divalproex
Runs in: United States · 1 site 		PHASE4
other		 COMPLETED 46 Nathan Kline Institute for Psychiatric Research
OTHER		 2006-03-29
Risperidone Augmentation for Treatment-Resistant Aggression in ADHD
NCT00297739
Risperidone
Runs in: United States · 1 site 		PHASE4
other		 COMPLETED 25 Armenteros, Jorge L., M.D., P.A.
OTHER		 2006-03-16
Memantine and Down's Syndrome
NCT00240760
Memantine Hydrochloride
Runs in: United Kingdom · 2 sites 		NA
symptomatic-cholinergic		 UNKNOWN 180 King's College London
OTHER		 2006-02-20
Study of the Effect of SR57667B in Patients With Alzheimer's Disease
NCT00285025
SR57667B 		PHASE2
other		 COMPLETED 500 Sanofi
INDUSTRY		 2006-02-01
MRS and DTI of White Matter in Alzheimer's Disease
NCT00172900
Runs in: Taiwan · 1 site 		NA
other		 UNKNOWN 40 National Taiwan University Hospital
OTHER		 2005-12-21
Safety and Efficacy of Galantamine in Patients With Dementia With Lewy Bodies
NCT00230997
Galantamine
Runs in: United States · 5 sites 		PHASE3
symptomatic-cholinergic		 COMPLETED 50 Neurological Research Center
INDUSTRY		 2005-12-16
CALM-AD
NCT00142324
Donepezil
Runs in: United Kingdom · 8 sites 		PHASE4
symptomatic-cholinergic		 UNKNOWN 190 Institute of Psychiatry, London
OTHER		 2005-12-14
Metabolic Syndrome, Inflammation, and Risk of Cognitive Decline
NCT00099567
Runs in: United States · 2 sites 		NA
other		 COMPLETED 2,632 National Institute on Aging (NIA)
NIH		 2005-11-01
Influence of Age on Hemispheric Lateralization of Language : a Longitudinal Study
NCT00241293
Runs in: France · 1 site 		NA
other		 COMPLETED — University Hospital, Tours
OTHER		 2005-10-18
Efficacy and Safety of Tetrabenazine in Chorea
NCT00219804
tetrabenazine or placebo 		PHASE3
other		 COMPLETED — Prestwick Pharmaceuticals
INDUSTRY		 2005-09-22
Double Blind Study of Trp01 in Patients With Alzheimer's Disease
NCT00202124
Tryptophan
Runs in: Canada · 1 site 		PHASE4
other		 COMPLETED 12 Queen's University
OTHER		 2005-09-20

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →