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Home › Research › Clinical trials

Clinical trials

Every Alzheimer's trial in our copy of the ClinicalTrials.gov registry — completed, running and abandoned. Filter it, then follow the link to the official record.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

Clear filters Download all 7,816 as CSV

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 7,701–7,725 of 7,816 matching trials · page 309 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
Effects of Lithium and Divalproex'on Brain-Derived Neurotrophic Factor in Huntington's Disease
NCT00095355
Lithium; Divalproex
Runs in: United States · 1 site 		PHASE2
other		 COMPLETED 35 National Institute of Neurological Disorders and Stroke (NINDS)
NIH		 2008-03-04
Preliminary Study of Fish Oil and Dementia
NCT00628017
omega-3 polyunsaturated fatty acids ( EPA+DHA)
Runs in: Taiwan · 1 site 		NA
other		 COMPLETED 46 Taipei City Psychiatric Center, Taiwan
OTHER		 2008-03-04
Donepezil in the Prevention of Post-Operative Cognitive Decline
NCT00182845
Donepezil
Runs in: United States · 1 site 		PHASE4
symptomatic-cholinergic		 COMPLETED 30 Pfizer
INDUSTRY		 2008-03-03
An Innovative Psychosocial Intervention for Adult-Child Caregivers of Parents With Alzheimer's Disease
NCT00409279
Information, counseling and support
Runs in: United States · 1 site 		NA
other		 UNKNOWN 100 The Jacob and Valeria Langeloth Foundation
OTHER		 2008-03-03
Huperzine A in Alzheimer's Disease
NCT00083590
Huperzine A
Runs in: United States · 29 sites 		PHASE2
other		 COMPLETED 150 National Institute on Aging (NIA)
NIH		 2008-02-21
TRx0014 in Patients With Mild or Moderate Alzheimer's Disease
NCT00515333
TRx0014; TRx0014; Placebo; TRx0014 		PHASE2
other		 COMPLETED 323 TauRx Therapeutics Ltd
INDUSTRY		 2008-02-20
Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SAM-315
NCT00474552
SAM-315
Runs in: France · 1 site 		PHASE1
other		 TERMINATED 56 Wyeth is now a wholly owned subsidiary of Pfizer
INDUSTRY		 2008-02-18
Efficacy Study for Treatment of Dementia in Progressive Supranuclear Palsy
NCT00522015
rivastigmine
Runs in: Germany · 1 site 		PHASE2
symptomatic-cholinergic		 UNKNOWN 20 University Hospital Tuebingen
OTHER		 2008-02-18
Treatment With Copper in Patients With Mild Alzheimer´s Dementia
NCT00608946
copper; placebo 		PHASE2
other		 COMPLETED 68 University Hospital, Saarland
OTHER		 2008-02-06
Prevention of Cognitive Decline in Alzheimer's Disease by Ingested Interferon Alpha
NCT00031018
Aricept; IFN-alpha2A
Runs in: United States · 1 site 		PHASE2
other		 UNKNOWN — National Center for Research Resources (NCRR)
NIH		 2008-02-05
A Randomized, Placebo-Controlled Trial to Examine the Efficacy of Oral Donepezil in Subjects With MCI
NCT00483028
donezepil (Aricept)
Runs in: United States · 2 sites 		NA
symptomatic-cholinergic		 COMPLETED 38 Pfizer
INDUSTRY		 2008-02-05
Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics Study of Bryostatin 1 in Patients With Alzheimer's Disease
NCT00606164
Bryostatin for Injection; Placebo
Runs in: United States · 1 site 		PHASE2
other		 UNKNOWN 9 Blanchette Rockefeller Neurosciences Insitute
OTHER		 2008-02-01
Short Term Effects of PRX-03140 in Patients With Mild Alzheimer's Disease Being Treated With Aricept
NCT00384423
PRX-03140
Runs in: United States · 17 sites 		PHASE2
other		 COMPLETED 80 Epix Pharmaceuticals, Inc.
INDUSTRY		 2008-01-30
Study Evaluating the Safety, Tolerability and Efficacy of PBT2 in Patients With Early Alzheimer's Disease
NCT00471211
PBT2
Runs in: Australia; Sweden · 15 sites 		PHASE2
other		 COMPLETED 80 Prana Biotechnology Limited
INDUSTRY		 2008-01-16
Nicotine Treatment of Mild Cognitive Impairment (MCI)
NCT00091468
Transdermal nicotine patch; Placebo transdermal patch
Runs in: United States · 3 sites 		PHASE1
other		 UNKNOWN 75 National Institute on Aging (NIA)
NIH		 2008-01-15
Study of Memantine in Assessment of Selected Measures of Volumetric Magnetic Resonance Imaging (MRI) and Cognition in Moderate AD (Alzheimer's Disease)
NCT00334906
memantine HCl
Runs in: United States · 1 site 		PHASE4
symptomatic-cholinergic		 COMPLETED 75 Forest Laboratories
INDUSTRY		 2008-01-07
Safety Study of the Novel Drug Dimebon to Treat Patients With Huntington's Disease
NCT00387270
Dimebon
Runs in: United States · 1 site 		PHASE1|PHASE2
other		 COMPLETED 9 Medivation, Inc.
INDUSTRY		 2008-01-04
The Impact of Lorazepam on Cognition in APOE e4 Carriers
NCT00586430
lorazepam; placebo
Runs in: United States · 1 site 		NA
other		 COMPLETED 36 Mayo Clinic
OTHER		 2008-01-04
Study Evaluating the Effect of Lecozotan SR on the QTc Interval
NCT00499642
Lecozotan SR; Moxifloxacin
Runs in: France · 2 sites 		PHASE1
other		 COMPLETED — Wyeth is now a wholly owned subsidiary of Pfizer
INDUSTRY		 2007-12-28
TREND-HD - A Trial of Ethyl-EPA (Miraxion™) in Treating Mild to Moderate Huntington's Disease
NCT00146211
Ethyl-EPA (Miraxion™)
Runs in: Canada; United States · 41 sites 		PHASE3
other		 COMPLETED 300 Amarin Neuroscience Ltd
INDUSTRY		 2007-12-27
Study of the Effects of Current Drug Treatments on Levels of Certain Brain Chemicals in Alzheimer's Disease
NCT00104442
Rivastigmine
Runs in: United States · 1 site 		PHASE4
symptomatic-cholinergic		 COMPLETED 80 Novartis
INDUSTRY		 2007-12-21
Safety and Tolerability of Rivastigmine With Add-on Memantine in Patients With Probable Alzheimer's Disease
NCT00305903
Rivastigmine, memantine
Runs in: United States · 1 site 		PHASE4
symptomatic-cholinergic		 COMPLETED 150 Novartis
INDUSTRY		 2007-12-21
Efficacy and Safety of Rivastigmine in Patients With Mild Cognitive Impairment
NCT00134953
Rivastigmine 		PHASE3
symptomatic-cholinergic		 TERMINATED 24 Novartis
INDUSTRY		 2007-12-17
Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Young and Elderly Subjects
NCT00480818
SAM-531
Runs in: France · 1 site 		PHASE1
other		 COMPLETED 80 Wyeth is now a wholly owned subsidiary of Pfizer
INDUSTRY		 2007-12-11
European Study of 3APS in Mild to Moderate Alzheimer's Disease Patients
NCT00217763
3APS
Runs in: Belgium; France; Germany; Italy; Netherlands; Poland; Spa... · 69 sites 		PHASE3
other		 UNKNOWN 930 Bellus Health Inc. - a GSK company
INDUSTRY		 2007-12-10

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →