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Home › Research › Clinical trials

Clinical trials

Every Alzheimer's trial in our copy of the ClinicalTrials.gov registry — completed, running and abandoned. Filter it, then follow the link to the official record.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

Clear filters Download all 7,816 as CSV

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 7,551–7,575 of 7,816 matching trials · page 303 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
AIT-082 Phase 1B Study
NCT00000180
AIT-082
Runs in: United States · 4 sites 		PHASE1
other		 COMPLETED — National Institute on Aging (NIA)
NIH		 2009-12-11
A Multicenter Trial of Rofecoxib and Naproxen in Alzheimer's Disease (NSAID Study)
NCT00004845
Rofecoxib; Naproxen
Runs in: United States · 40 sites 		PHASE2|PHASE3
anti-inflammatory		 COMPLETED — National Institute on Aging (NIA)
NIH		 2009-12-11
The Safety and Efficacy of an Investigational Drug in Delaying the Progression of Alzheimer's Disease
NCT00006187
Investigational drug
Runs in: United States · 34 sites 		PHASE3
other		 TERMINATED — Merck Sharp & Dohme LLC
INDUSTRY		 2009-12-11
Effectiveness of A Nutritional Brain Metabolic Enhancer for Alzheimer Disease
NCT00013923
Nutritional Supplement
Runs in: United States · 1 site 		PHASE2
other		 COMPLETED 40 National Institute on Aging (NIA)
NIH		 2009-12-11
Gene Therapy for Alzheimer's Disease Clinical Trial
NCT00017940
Human Nerve Growth Factor
Runs in: United States · 1 site 		PHASE1
gene-therapy		 COMPLETED 8 The Shiley Family Trust
OTHER		 2009-12-11
Treatment of Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)
NCT00043849
Quetiapine
Runs in: United States · 21 sites 		PHASE4
other		 COMPLETED 60 National Institute on Aging (NIA)
NIH		 2009-12-11
Alzheimer's Disease Treatment and Illness Perceptions Survey (TIPS) II
NCT00059410
Runs in: United States · 1 site 		NA
other		 COMPLETED 210 Alzheimer's Association
OTHER		 2009-12-11
ALADDIN Study: Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation
NCT00063310
Leuprolide acetate
Runs in: United States · 3 sites 		PHASE2
other		 COMPLETED 90 Voyager Pharmaceutical Corporation
INDUSTRY		 2009-12-11
Antigonadotropin-Leuprolide in Alzheimer's Disease Drug INvestigation (ALADDIN) VP 104 Study
NCT00076440
Leuprolide acetate
Runs in: United States · 13 sites 		PHASE2
other		 COMPLETED 90 Voyager Pharmaceutical Corporation
INDUSTRY		 2009-12-11
SGS742 in Patients With Mild to Moderate Alzheimer's Disease (AD)
NCT00093951
SGS742
Runs in: United States · 59 sites 		PHASE2
other		 COMPLETED 280 Saegis Pharmaceuticals
INDUSTRY		 2009-12-11
Mifepristone as Adjunctive Therapy in Alzheimer's Disease
NCT00105105
Mifepristone
Runs in: United States · 21 sites 		PHASE2
other		 TERMINATED 160 Corcept Therapeutics
INDUSTRY		 2009-12-11
A Trial of SK-PC-B70M in Mild to Moderate Alzheimer's Disease
NCT00443417
SK-PC-B70M
Runs in: South Korea · 1 site 		PHASE2
other		 COMPLETED 188 SK Chemicals Co., Ltd.
INDUSTRY		 2009-12-09
Brain Uptake and Safety With Probable Alzheimer's Disease, Amnestic Mild Cognitive Impairment and Healthy Volunteers
NCT00785759
AH110690 (18F) Injection
Runs in: Norway · 1 site 		PHASE2
other		 COMPLETED 78 GE Healthcare
INDUSTRY		 2009-12-07
Study Of Single Ascending And Multiple Doses Of PF-04447943 In Japanese Subjects.
NCT00959803
PF-04447943; PF-04447943; PF-04447943; Placebo; PF-04447943; Placebo
Runs in: United States · 1 site 		PHASE1
other		 COMPLETED 17 Pfizer
INDUSTRY		 2009-12-07
Curcumin in Patients With Mild to Moderate Alzheimer's Disease
NCT00099710
Curcumin C3 Complex
Runs in: United States · 1 site 		PHASE2
other		 COMPLETED 33 John Douglas French Foundation
OTHER		 2009-12-03
Alzheimer's Caregiver Communication Study
NCT00182988
Runs in: United States · 1 site 		NA
other		 COMPLETED 140 National Institute on Aging (NIA)
NIH		 2009-11-25
A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers
NCT00931073
Dimebon alone; Dimebon + Ketoconazole; Dimebon + Omeprazole
Runs in: United States · 1 site 		PHASE1
other		 COMPLETED 24 Pfizer
INDUSTRY		 2009-11-18
Huperzine-A to Help With Mental Problems and the Inability to Care for Onself in Patients With Schizophrenia
NCT01012830
Huperzine A
Runs in: United States · 1 site 		PHASE4
other		 UNKNOWN 15 VA Nebraska Western Iowa Health Care System
OTHER_GOV		 2009-11-13
Safety Study of a Glycogen Synthase Kinase 3 (GSK3) Inhibitor in Patients With Alzheimer´s Disease
NCT00948259
NP031112; Placebo
Runs in: Germany · 3 sites 		PHASE1|PHASE2
other		 COMPLETED 30 Noscira SA
INDUSTRY		 2009-11-11
The Use of Reminders in Implementing an E-learning Program in General Practice
NCT00394017
Reminder letters
Runs in: Denmark · 1 site 		NA
other		 COMPLETED 339 Research Unit Of General Practice, Copenhagen
OTHER		 2009-10-27
Positron Emission Tomography (PET) Study With [18F]AZD4694 and [11C]AZD2184, Candidate PET Ligands for Aβ Amyloid
NCT00838877
radioligand [18F]AZD4694; radioligand [11C]AZD2184
Runs in: Sweden · 2 sites 		PHASE1
other		 COMPLETED 26 AstraZeneca
INDUSTRY		 2009-10-23
A Phase I, Single IV Dose Of PF-04360365 In Adults With Mild To Moderate Alzheimer's Disease
NCT00455000
PF-04360365; Placebo
Runs in: Australia; Canada; Sweden; United Kingdom · 12 sites 		PHASE1
other		 COMPLETED 37 Pfizer
INDUSTRY		 2009-10-14
Effects of LY2062430 in Subjects With Mild-to-Moderate Alzheimer's Disease and in Healthy Volunteers
NCT00329082
LY2062430; Placebo
Runs in: United States · 6 sites 		PHASE2
other		 COMPLETED 25 Eli Lilly and Company
INDUSTRY		 2009-10-07
Study Evaluating the Safety,Tolerability, PK and PD of SAM-531 in the Subjects With Mild to Moderate Alzheimer's Disease
NCT00481520
SAM-531; placebo
Runs in: United States · 7 sites 		PHASE2
other		 COMPLETED 72 Wyeth is now a wholly owned subsidiary of Pfizer
INDUSTRY		 2009-09-30
Quetiapine Extended Release (XR) for the Management of Psychotic Aggression or Agitation in Adult Acute Psychiatry
NCT00986167
Quetiapine XR
Runs in: Australia · 2 sites 		PHASE4
other		 UNKNOWN 72 Bayside Health
OTHER_GOV		 2009-09-29

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →