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Home › Research › Clinical trials

Clinical trials

Every Alzheimer's trial in our copy of the ClinicalTrials.gov registry — completed, running and abandoned. Filter it, then follow the link to the official record.

If you are thinking about joining a trial

A listing here is a record that a study was registered. It is not a recommendation, and it does not mean the study is still recruiting or that anyone is eligible. Registry entries go stale.

Talk to the treating doctor first, then contact the study team listed on the official ClinicalTrials.gov record. The NIA's free referral line can help you look: 1-800-438-4380, weekdays, English and Spanish.

Clear filters Download all 7,816 as CSV

"Open to new participants" means the registry status is RECRUITING or NOT_YET_RECRUITING — 1,523 of the 7,816 records. That is what the sponsor last told the registry, which can be months out of date.
Location is by country. This pull of the registry records the countries a study runs in, not its individual sites, so we cannot filter by US state or city — and we are not going to guess one. To find the nearest site, open a trial's record below: the official page lists every location with its contact details.

Showing 401–425 of 7,816 matching trials · page 17 of 313, 25 per page.

Sorted by the date the registry record was last updated, newest first. This page never loads all 7,816 rows at once — use the CSV download if you want the whole file.

Registered Alzheimer's clinical trials. Every ID links to its official ClinicalTrials.gov record.
Trial Phase Status Enrolled Sponsor Last updated
Metformin in Alzheimer's Dementia Prevention
NCT04098666
Placebo oral tablet; extended release metformin
Runs in: United States · 22 sites 		PHASE2|PHASE3
other		 ACTIVE_NOT_RECRUITING 326 Columbia University
OTHER		 2026-08-11
Sub-Lingual Dexmedetomidine in Agitation Associated With Dementia
NCT04251910
Sublingual film containing Dexmedetomidine; Sublingual Placebo Film
Runs in: United States · 5 sites 		PHASE1|PHASE2
other		 COMPLETED 100 BioXcel Therapeutics Inc
INDUSTRY		 2026-08-11
Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia
NCT04268303
Sublingual film containing dexmedetomidine (BXCL501); Placebo Film
Runs in: United States · 15 sites 		PHASE3
other		 COMPLETED 380 BioXcel Therapeutics Inc
INDUSTRY		 2026-08-11
Dexmedetomidine in the Treatment of Agitation Associated With Bipolar Disorder
NCT04276883
Sublingual film containing Dexmedetomidine (BXCL501); Placebo Film
Runs in: United States · 15 sites 		PHASE3
other		 COMPLETED 380 BioXcel Therapeutics Inc
INDUSTRY		 2026-08-11
Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid Withdrawal
NCT04470050
Dexmedetomidine; Placebo
Runs in: United States · 3 sites 		PHASE1|PHASE2
other		 COMPLETED 225 BioXcel Therapeutics Inc
INDUSTRY		 2026-08-11
Semantic Rehabilitation for Patients With Primary Progressive Semantic Aphasia
NCT04957537
semantic therapy and semantic re-education
Runs in: France · 1 site 		NA
other		 RECRUITING 15 University Hospital, Toulouse
OTHER		 2026-08-11
Interventions in Mathematics and Cognitive Skills
NCT05201534
Interventions in Mathematics and Cognitive Skills - Experimental; I...
Runs in: United States · 1 site 		NA
other		 RECRUITING 180 Stanford University
OTHER		 2026-08-11
Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY II)
NCT05271552
BXCL501; Matching Placebo
Runs in: United States · 11 sites 		PHASE3
other		 COMPLETED 151 BioXcel Therapeutics Inc
INDUSTRY		 2026-08-11
An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With Dementia
NCT05276830
BXCL501; BXCL501; Placebo film
Runs in: United States · 3 sites 		PHASE2
other		 TERMINATED 5 BioXcel Therapeutics Inc
INDUSTRY		 2026-08-11
Study of BXCL501 In Agitation Associated With Delirium in ICU Patients
NCT05313386
BXCL501; Placebo film
Runs in: United States · 1 site 		PHASE2
other		 WITHDRAWN 0 BioXcel Therapeutics Inc
INDUSTRY		 2026-08-11
Neuromodulation of Memory in Aging
NCT05460468
Transcranial Magnetic Stimulation
Runs in: United States · 1 site 		NA
other		 RECRUITING 150 Indiana University
OTHER		 2026-08-11
Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar Disorder
NCT06041646
Sublingual film containing Igalmi
Runs in: United States · 2 sites 		PHASE4
other		 COMPLETED 29 BioXcel Therapeutics Inc
INDUSTRY		 2026-08-11
Comprehensive Dementia Management : From Translational Medicine to Innovative Care
NCT06214962
(multiple training modalities, MTM)
Runs in: Taiwan · 1 site 		NA
other		 COMPLETED 652 Kaohsiung Medical University Chung-Ho Memorial Hospital
OTHER		 2026-08-11
Compass for Care: A Theory-driven Mobile Solution to Promote Well-being Among Caregivers of Individuals With ADRD
NCT06249139
Compass for Care (Well-being intervention); Compass for Care (Safet...
Runs in: United States · 1 site 		NA
other		 COMPLETED 278 Pro-Change Behavior Systems
OTHER		 2026-08-11
To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)
NCT07116473
Acoramidis (AG10) 		PHASE3
other		 NOT_YET_RECRUITING 250 Eidos Therapeutics, a BridgeBio company
INDUSTRY		 2026-08-11
A Study To Assess The Feasibility Of Indivi Mobile Application In Monitoring Cognitive Performance In Aging Population
NCT07174869
Runs in: United States · 1 site 		NA
other		 COMPLETED 32 Indivi AG
INDUSTRY		 2026-08-11
Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)
NCT07204977
Acamprosate calcium
Runs in: United States · 1 site 		PHASE1
other		 ACTIVE_NOT_RECRUITING 30 National Institute of Neurological Disorders and Stroke (NINDS)
NIH		 2026-08-11
ALDH2 Genetic Testing in East Asian Community
NCT07392775
Genetic Test Results Return; Alcohol Flushing Education
Runs in: United States · 1 site 		NA
other		 NOT_YET_RECRUITING 100 Northwestern University
OTHER		 2026-08-11
Lived Experience Narratives in Dementia
NCT07757178
Online LEND Intervention
Runs in: United Kingdom · 2 sites 		NA
other		 RECRUITING 60 University of Nottingham
OTHER		 2026-08-11
Safety Assessment of H2 Inhalation in Patients With Mild Cognitive Impairment
NCT07757542
Molecular hydrogen inhalation
Runs in: Czechia · 1 site 		PHASE2
other		 RECRUITING 34 University of Ostrava
OTHER		 2026-08-11
Alzheimer's Disease Research Center (ADRC) PET Component Study
NCT07758660
18F-MK6240; 18F-Florbetaben (FBB)
Runs in: United States · 1 site 		PHASE2
other		 ENROLLING_BY_INVITATION 120 Patrick Lao
OTHER		 2026-08-11
Primary Care Screening and Intervention for Patients With Dementia and Caregivers
NCT07758738
SIRENS application; SIRENS screening
Runs in: United States · 1 site 		NA
other		 NOT_YET_RECRUITING 774 Weill Medical College of Cornell University
OTHER		 2026-08-11
Multisensory 40-Hz Stimulation for Alzheimer's Disease
NCT07758751
Multisensory 40-Hz Stimulation Device; Sham Multisensory Stimulation 		NA
other		 NOT_YET_RECRUITING 60 Beijing Tiantan Hospital
OTHER		 2026-08-11
Network-targeted Theta-burst Stimulation for Episodic Memory Improvement in Mild Cognitive Impairment
NCT04558164
Active Theta Burst Stimulation; Sham Theta Burst Stimulation
Runs in: United States · 1 site 		NA
other		 ACTIVE_NOT_RECRUITING 70 University of California, Los Angeles
OTHER		 2026-08-10
The SINgapore GERiatric Intervention Study to Reduce Cognitive Decline and Physical Frailty (SINGER) Study
NCT05007353
Structured Lifestyle Intervention; Self-Guided Intervention
Runs in: Singapore · 3 sites 		NA
other		 COMPLETED 1,212 National University of Singapore
OTHER		 2026-08-10

This table is wider than a phone screen — swipe it sideways to see the rest.

Where these trials come from

Registry
ClinicalTrials.gov, pulled through their public API (v2)
Trials in the file
7,816
Source file
trials.csv (3.8 MB, 7816 rows)
Basis
Measured These are registry records as submitted by each study's sponsor.

What could make this misleading

Sponsors enter their own data and do not always keep it current, so "recruiting" can be out of date by months or years. Enrollment figures may be targets rather than actual numbers; the downloaded file says which for each trial. Trials that were never registered do not appear at all, and the intervention class is this project's own grouping, not the registry's.

Always check the official record before acting on anything here. This is a summary, not medical advice.

Related evidence Treatments → What the drugs that finished their trials actually achieved.

From the research library

The highest-scoring studies we hold on this subject, each summarised in plain English. Scores are alzhub's usefulness score, not a verdict on the science.

Clinical trials

All 162 studies on Clinical trials →