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Home › Research › Topics › wild-type-mice

wild-type-mice

2 studies tagged wild-type-mice, dated 2015-03-02 to 2016-01-12. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Alzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression 2016-01-12
  2. GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease 2015-03-02

Studies

2 studies carry this tag.

Date range

2015 to 2016

Top journals

  • Glia 1
  • Molecular neurodegeneration 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Alzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Molecular neurodegeneration 2016-01-12 Biomarkers

    This demonstrates that an AD-like APP processing, yielding to levels of APP, βCTF and Aβ42/Aβ40 ratio similar to those observed in AD patients, are sufficient to rapidly trigger early steps of the amyloidogenic and Tau pathways in vivo.

  2. GFAP and vimentin deficiency alters gene expression in astrocytes and microglia in wild-type mice and changes the transcriptional response of reactive glia in mouse model for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Glia 2015-03-02 Biomarkers

    Reactive astrocytes with an increased expression of intermediate filament (IF) proteins Glial Fibrillary Acidic Protein (GFAP) and Vimentin (VIM) surround amyloid plaques in Alzheimer's disease (AD).

All topic tags with their study counts