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Newest in this topic

  1. Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome 2021-06-25
  2. Mechanistic insights into the deleterious roles of Nasu-Hakola disease associated TREM2 variants 2020-02-27
  3. Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes 2014-06-20

Studies

4 studies carry this tag.

Date range

2014 to 2021

Top journals

  • Scientific reports 2
  • Neurobiology of aging 1
  • PloS one 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Scientific reports 2021-06-25 TREM2 and immune genetics

    The R47H variant of the microglial membrane receptor TREM2 is linked to increased risk of late onset Alzheimer's disease.

  2. Mechanistic insights into the deleterious roles of Nasu-Hakola disease associated TREM2 variants

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Scientific reports 2020-02-27 TREM2 and immune genetics

    Recently, the critical roles played by genetic variants of TREM2 (Triggering Receptor Expressed on Myeloid cells 2) in Alzheimer's disease have been aggressively highlighted.

  3. Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes

    ✓ Peer-reviewed alzhub usefulness score 45 out of 100. Neurobiology of aging 2014-06-20 TREM2 and immune genetics

    Frontotemporal dementia (FTD) is a clinically and genetically heterogeneous disorder.

  4. Evidence of trem2 variant associated with triple risk of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. PloS one 2014-03-24 TREM2 and immune genetics

    Alzheimer's disease is one of the main causes of dementia among elderly individuals and leads to the neurodegeneration of different areas of the brain, resulting in memory impairments and loss of cognitive functions.

All topic tags with their study counts