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Newest in this topic

  1. APOE and Alzheimer's Disease: From Lipid Transport to Physiopathology and Therapeutics 2021-02-17
  2. Retrograde transport of γ-secretase from endosomes to the trans-Golgi network regulates Aβ42 production 2018-08-16
  3. Apolipoprotein E: from lipid transport to neurobiology 2010-09-18

Studies

5 studies carry this tag.

Date range

1996 to 2021

Top journals

  • Frontiers in neuroscience 1
  • Journal of neurochemistry 1
  • Proceedings of the National Academy of Sciences of the United States of America 1
  • Progress in lipid research 1
  • The Journal of pharmacy and pharmacology 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. APOE and Alzheimer's Disease: From Lipid Transport to Physiopathology and Therapeutics

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Frontiers in neuroscience 2021-02-17 Tau biomarkers

    Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by extracellular amyloid β (Aβ) and intraneuronal tau protein aggregations.

  2. Retrograde transport of γ-secretase from endosomes to the trans-Golgi network regulates Aβ42 production

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of neurochemistry 2018-08-16 Biomarkers

    The aberrant metabolism of amyloid-β protein (Aβ) in the human brain has been implicated in the etiology of Alzheimer disease (AD). γ-Secretase is the enzyme that generates various forms of Aβ, such as Aβ40 and Aβ42, the latter being an aggregation-prone toxic peptide that is involved in the pathogenesis of AD.

  3. Apolipoprotein E: from lipid transport to neurobiology

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Progress in lipid research 2010-09-18 Genetics

    Apolipoprotein (apo) E has a storied history as a lipid transport protein.

  4. Is nose-to-brain transport of drugs in man a reality?

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of pharmacy and pharmacology 2004-01-01 Tau biomarkers

    The blood-brain barrier that segregates the brain interstitial fluid from the circulating blood provides an efficient barrier for the diffusion of most, especially polar, drugs from the blood to receptors in the central nervous system (CNS).

  5. Glycoprotein 330/megalin: probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer disease amyloid beta at the blood-brain and blood-cerebrospinal fluid barriers

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 1996-04-01 Tau biomarkers

    A soluble form of Alzheimer disease amyloid beta-protein (sA beta) is transported in the blood and cerebrospinal fluid mainly complexed with apolipoprotein J (apoJ).

All topic tags with their study counts