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transport
5 studies tagged transport, dated 1996-04-01 to 2021-02-17. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
Studies
5 studies carry this tag.
Date range
1996 to 2021
Top journals
- Frontiers in neuroscience 1
- Journal of neurochemistry 1
- Proceedings of the National Academy of Sciences of the United States of America 1
- Progress in lipid research 1
- The Journal of pharmacy and pharmacology 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by extracellular amyloid β (Aβ) and intraneuronal tau protein aggregations.
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The aberrant metabolism of amyloid-β protein (Aβ) in the human brain has been implicated in the etiology of Alzheimer disease (AD). γ-Secretase is the enzyme that generates various forms of Aβ, such as Aβ40 and Aβ42, the latter being an aggregation-prone toxic peptide that is involved in the pathogenesis of AD.
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Apolipoprotein (apo) E has a storied history as a lipid transport protein.
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The blood-brain barrier that segregates the brain interstitial fluid from the circulating blood provides an efficient barrier for the diffusion of most, especially polar, drugs from the blood to receptors in the central nervous system (CNS).
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A soluble form of Alzheimer disease amyloid beta-protein (sA beta) is transported in the blood and cerebrospinal fluid mainly complexed with apolipoprotein J (apoJ).