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toxicity
3 studies tagged toxicity, dated 2001-05-01 to 2019-05-24. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Galectin-3 promotes Aβ oligomerization and Aβ toxicity in a mouse model of Alzheimer's disease 2019-05-24
- Antiamnesic and neuroprotective effects of the aminotetrahydrofuran derivative ANAVEX1-41 against amyloid beta(25-35)-induced toxicity in mice 2008-12-03
- Aluminium toxicity in the rat brain: histochemical and immunocytochemical evidence 2001-05-01
Studies
3 studies carry this tag.
Date range
2001 to 2019
Top journals
- Brain research bulletin 1
- Cell death and differentiation 1
- Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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41/100
Amyloid-β (Aβ) oligomers largely initiate the cascade underlying the pathology of Alzheimer's disease (AD).
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The antiamnesic and neuroprotective activities of the new aminotetrahydrofuran derivative tetrahydro-N,N-dimethyl-5,5-diphenyl-3-furanmethanamine hydrochloride (ANAVEX1-41), a nonselective muscarinic receptor ligand and sigma1 protein activator, were examined in mice injected intracerebroventricularly with amyloid beta(25-35) (Abeta(25-35)) peptide (9 nmol).
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Although the neurotoxic actions of aluminium (Al) have been well documented, its contribution to neurodegenerative diseases such as Alzheimer's disease remains controversial.