Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest in this topic

  1. Hemispheric asymmetry of tau pathology is related to asymmetric amyloid deposition in Alzheimer's Disease 2025-09-05
  2. APOE4 impact on soluble and insoluble tau pathology is mostly influenced by amyloid-β 2025-07-01
  3. Risk of conversion to mild cognitive impairment or dementia among subjects with amyloid and tau pathology: a systematic review and meta-analysis 2024-04-12

Studies

6 studies carry this tag.

Date range

2022 to 2025

Top journals

  • Alzheimer's research & therapy 1
  • Brain : a journal of neurology 1
  • Frontiers in aging neuroscience 1
  • Molecular psychiatry 1
  • Nature aging 1

6 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Hemispheric asymmetry of tau pathology is related to asymmetric amyloid deposition in Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Nature communications 2025-09-05 Biomarkers

    The distribution of tau pathology in Alzheimer's disease (AD) shows remarkable inter-individual heterogeneity, including hemispheric asymmetry.

  2. APOE4 impact on soluble and insoluble tau pathology is mostly influenced by amyloid-β

    ✓ Peer-reviewed alzhub usefulness score 72 out of 100. Brain : a journal of neurology 2025-07-01 Biomarkers

    Although APOE4 is strongly associated with amyloid-β (Aβ), its relationship with tau accumulation is less understood.

  3. Risk of conversion to mild cognitive impairment or dementia among subjects with amyloid and tau pathology: a systematic review and meta-analysis

    ✓ Peer-reviewed alzhub usefulness score 83 out of 100. Alzheimer's research & therapy 2024-04-12 Biomarkers

    Identifying Aβ-positive individuals, irrespective of the measurement technique employed (CSF or PET), enables the detection of the most at-risk population before disease onset, or at least at a mild stage.

  4. Tau pathology is associated with synaptic density and longitudinal synaptic loss in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Molecular psychiatry 2024-04-08 Biomarkers

    The associations of synaptic loss with amyloid-β (Aβ) and tau pathology measured by positron emission tomography (PET) and plasma analysis in Alzheimer's disease (AD) patients are unknown.

  5. APOEε4 potentiates amyloid β effects on longitudinal tau pathology

    ✓ Peer-reviewed alzhub usefulness score 66 out of 100. Nature aging 2023-09-25 Biomarkers

    The mechanisms by which the apolipoprotein E ε4 (APOEε4) allele influences the pathophysiological progression of Alzheimer's disease (AD) are poorly understood.

  6. Microglial Activation, Tau Pathology, and Neurodegeneration Biomarkers Predict Longitudinal Cognitive Decline in Alzheimer's Disease Continuum

    ✓ Peer-reviewed alzhub usefulness score 67 out of 100. Frontiers in aging neuroscience 2022-06-30 Biomarkers

    Baseline CSF Aβ42/Aβ40 ratio was decreased in MCI and AD compared to CN, while CSF p-tau181 and t-tau increased.

All topic tags with their study counts