alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Home › Research › Topics › significance

significance

5 studies tagged significance, dated 1995-03-01 to 2022-06-03. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Expression relationship and significance of NEAT1 and miR-27a-3p in serum and cerebrospinal fluid of patients with Alzheimer's disease 2022-06-03
  2. Alzheimer's Disease Variants with the Genome-Wide Significance are Significantly Enriched in Immune Pathways and Active in Immune Cells 2016-01-09
  3. Cerebral Microbleeds, CSF p-Tau, and Cognitive Decline: Significance of Anatomic Distribution 2015-07-30

Studies

5 studies carry this tag.

Date range

1995 to 2022

Top journals

  • AJNR. American journal of neuroradiology 1
  • BMC neurology 1
  • Journal of neuropathology and experimental neurology 1
  • Molecular neurobiology 1
  • Neuroscience letters 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Expression relationship and significance of NEAT1 and miR-27a-3p in serum and cerebrospinal fluid of patients with Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 50 out of 100. BMC neurology 2022-06-03 Biomarkers

    The MMSE score, MoCA score, serum miR-27a-3p level, cerebrospinal fluid miR-27a-3p, Aβ42 levels and Aβ42/Aβ40 ratio of AD patients in mild group and moderate-to-severe group were all lower than those in the control group, and the moderate-to-severe group were lower than the mild group (all P < 0.05);the serum NEAT1 level, SUVR, and cerebrospinal fluid NEAT1 and BACE1 levels were higher than those in the control group, and the moderate-to-severe group were higher than the mild group (all P < 0.05).

  2. Alzheimer's Disease Variants with the Genome-Wide Significance are Significantly Enriched in Immune Pathways and Active in Immune Cells

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Molecular neurobiology 2016-01-09 Genetics

    The existing large-scale genome-wide association studies (GWAS) datasets provide strong support for investigating the mechanisms of Alzheimer's disease (AD) by applying multiple methods of pathway analysis.

  3. Cerebral Microbleeds, CSF p-Tau, and Cognitive Decline: Significance of Anatomic Distribution

    ✓ Peer-reviewed alzhub usefulness score 60 out of 100. AJNR. American journal of neuroradiology 2015-07-30 Biomarkers

    The distribution of microbleeds revealed different associations with amyloid-β and phosphorylated tau 181 protein levels and cognition.

  4. Significance and confounders of peripheral DJ-1 and alpha-synuclein in Parkinson's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Neuroscience letters 2010-06-09 Tau biomarkers

    DJ-1 and alpha-synuclein are leading biomarkers for Parkinson's disease diagnosis and/or monitoring disease progression.

  5. Interleukin-1 expression in different plaque types in Alzheimer's disease: significance in plaque evolution

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of neuropathology and experimental neurology 1995-03-01 Risk genes beyond APOE

    The histologically apparent polymorphism of plaques containing beta-amyloid in Alzheimer's disease is thought to represent different stages in plaque evolution. beta-amyloid-immunopositive plaques were classified according to the pattern of beta-amyloid distribution (diffuse vs dense-core) and the presence or absence of dystrophic beta-amyloid precursor protein-immunopositive (beta-APP+) neurites (neuritic vs non-neuritic).

All topic tags with their study counts