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signatures
4 studies tagged signatures, dated 2017-06-19 to 2024-01-12. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition 2024-01-12
- A peripheral signature of Alzheimer's disease featuring microbiota-gut-brain axis markers 2023-05-31
- The CSF neurofilament light signature in rapidly progressive neurodegenerative dementias 2018-01-11
Studies
4 studies carry this tag.
Date range
2017 to 2024
Top journals
- Alzheimer's research & therapy 2
- Molecular psychiatry 1
- PloS one 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Neuroinflammation is a hallmark of Alzheimer's disease (AD) and both positive and negative associations of individual inflammation-related markers with brain structure and cognitive function have been described.
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This study tests the hypothesis that GM and mediators of the microbiota-gut-brain axis (MGBA) are associated with the amyloid cascade in sporadic AD.
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The present data indicate that CSF NfL and t-tau levels reflect distinct pathophysiological mechanisms of neurodegeneration and support the clinical use of NfL as a fast screening biomarker for the differential diagnosis of atypical/rapidly progressive NDs.
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In the diagnosis of Alzheimer's disease (AD) total tau (T-tau), tau phosphorylated at threonine 181 (P-tau181), and the 42 amino acid isoform of alpha β-amyloid (Aβ) are well established surrogate CSF markers.