Home › Research › Topics › shared-genetic
shared-genetic
6 studies tagged shared-genetic, dated 2015-06-23 to 2022-07-18. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer's disease and gastrointestinal tract disorders 2022-07-18
- Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimer's disease and Parkinson's disease: a large-scale multi-trait association analysis 2022-06-22
- Shared genetic etiology underlying Alzheimer's disease and major depressive disorder 2020-03-09
Studies
6 studies carry this tag.
Date range
2015 to 2022
Top journals
- Acta neuropathologica 1
- Annals of neurology 1
- BMC medicine 1
- Communications biology 1
- Molecular aspects of medicine 1
6 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
-
Consistent with the concept of the gut-brain phenomenon, observational studies suggest a relationship between Alzheimer's disease (AD) and gastrointestinal tract (GIT) disorders; however, their underlying mechanisms remain unclear.
-
Our findings provide novel insights into the genetic determinants of LBD and the shared genetic etiology and biological mechanisms of LBD, AD, and PD, which could benefit the understanding of the co-pathology as well as the potential treatment of these diseases simultaneously.
-
Patients with late-onset Alzheimer's disease (LOAD) frequently manifest comorbid neuropsychiatric symptoms with depression and anxiety being most frequent, and individuals with major depressive disorder (MDD) have an increased prevalence of LOAD.
-
Corticobasal degeneration (CBD), progressive supranuclear palsy (PSP) and a subset of frontotemporal dementia (FTD) are neurodegenerative disorders characterized by tau inclusions in neurons and glia (tauopathies).
-
Our findings indicate shared genetic susceptibility to AD and small vessel stroke and highlight potential causal pathways and loci.
-
Epidemiological evidence supports the observation that subjects with type 2 diabetes (T2D) are at higher risk to develop Alzheimer's disease (AD).