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Home › Research › Topics › regions

regions

3 studies tagged regions, dated 2002-08-26 to 2019-11-26. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Neurodegenerative Disease-Associated Variants in TREM2 Destabilize the Apical Ligand-Binding Region of the Immunoglobulin Domain 2019-11-26
  2. Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity 2005-12-12
  3. An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript 2002-08-26

Studies

3 studies carry this tag.

Date range

2002 to 2019

Top journals

  • Frontiers in neurology 1
  • Proceedings of the National Academy of Sciences of the United States of America 1
  • The Journal of biological chemistry 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Neurodegenerative Disease-Associated Variants in TREM2 Destabilize the Apical Ligand-Binding Region of the Immunoglobulin Domain

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Frontiers in neurology 2019-11-26 TREM2 and immune genetics

    Single nucleotide variations in Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) have been linked to both late-onset Alzheimer's disease and behavioral variant frontotemporal dementia (FTD), the latter presenting either in isolation or with cystic bone lesions in a condition called Nasu-Hakola disease.

  2. Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2005-12-12 Genetics

    Apolipoprotein (apo) E4, a 299-aa protein and a major risk factor for Alzheimer's disease, can be cleaved to generate C-terminal-truncated fragments that cause neurotoxicity in vitro and neurodegeneration and behavioral deficits in transgenic mice.

  3. An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of biological chemistry 2002-08-26 Risk genes beyond APOE

    Iron-responsive elements (IREs) are the RNA stem loops that control cellular iron homeostasis by regulating ferritin translation and transferrin receptor mRNA stability.

All topic tags with their study counts