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Home › Research › Topics › r47h-trem2

r47h-trem2

2 studies tagged r47h-trem2, dated 2021-06-25 to 2022-12-08. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Alzheimer's disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss 2022-12-08
  2. Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome 2021-06-25

Studies

2 studies carry this tag.

Date range

2021 to 2022

Top journals

  • Glia 1
  • Scientific reports 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Alzheimer's disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Glia 2022-12-08 TREM2 and immune genetics

    Triggering receptor on myeloid cells 2 (TREM2) is an innate immune receptor, upregulated on the surface of microglia associated with amyloid plaques in Alzheimer's disease (AD).

  2. Microglial signalling pathway deficits associated with the patient derived R47H TREM2 variants linked to AD indicate inability to activate inflammasome

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. Scientific reports 2021-06-25 TREM2 and immune genetics

    The R47H variant of the microglial membrane receptor TREM2 is linked to increased risk of late onset Alzheimer's disease.

All topic tags with their study counts