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Home › Research › Topics › progranulin

progranulin

2 studies tagged progranulin, dated 2010-11-18 to 2021-09-01. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Effect of the Histone Deacetylase Inhibitor FRM-0334 on Progranulin Levels in Patients With Progranulin Gene Haploinsufficiency: A Randomized Clinical Trial 2021-09-01
  2. Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma 2010-11-18

Studies

2 studies carry this tag.

Date range

2010 to 2021

Top journals

  • American journal of human genetics 1
  • JAMA network open 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Effect of the Histone Deacetylase Inhibitor FRM-0334 on Progranulin Levels in Patients With Progranulin Gene Haploinsufficiency: A Randomized Clinical Trial

    ✓ Peer-reviewed alzhub usefulness score 84 out of 100. JAMA network open 2021-09-01 Biomarkers

    In a cross-sectional analysis of 26 individuals, bifrontal cortical FDG hypometabolism was associated with worse Clinical Dementia Rating (CDR) plus National Alzheimer's Coordinating Center frontotemporal lobar degeneration sum of boxes score (b = -3.6 × 10-2 standardized uptake value ratio [SUVR] units/CDR units; 95% CI, -4.9 × 10-2 to -2.2 × 10-2; P < .001), high cerebrospinal fluid NfL (b = -9.2 × 10-5 SUVR units/pg NfL/mL; 95% CI, -1.3 × 10-4 to -5.6 × 10-5; P < .001), and high CSF t-tau (-7.2 × 10-4 SUVR units/pg t-tau/mL; 95% CI, -1.4 × 10-3 to -9.5 × 10-5; P = .03).

  2. Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. American journal of human genetics 2010-11-18 Genetics

    Recent studies suggest progranulin (GRN) is a neurotrophic factor.

All topic tags with their study counts