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processing
3 studies tagged processing, dated 1996-12-01 to 2013-01-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Age-related changes in brain extracellular space affect processing of amyloid-β peptides in Alzheimer's disease 2013-01-01
- Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction 2011-06-01
- Beta-secretase processing of the beta-amyloid precursor protein in transgenic mice is efficient in neurons but inefficient in astrocytes 1996-12-01
Studies
3 studies carry this tag.
Date range
1996 to 2013
Top journals
- Annals of neurology 1
- Journal of Alzheimer's disease : JAD 1
- The Journal of biological chemistry 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Alzheimer's disease is a neurodegenerative disease in which aging is not only a major risk factor but a major determinant of onset, course, and pathogenesis.
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These results suggest that some SAD may involve alternative processing of multiple γ-secretase substrates, raising the possibility that the molecular pathogenesis of SAD might involve γ-secretase dysfunction.
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Alzheimer's disease is characterized by the extracellular deposition of beta-amyloid peptide (Abeta) in cerebral plaques and evidence is accumulating that amyloid is neurotoxic.