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Home › Research › Topics › presenilin-1

presenilin-1

2 studies tagged presenilin-1, dated 2007-11-01 to 2016-02-04. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. The dynamic mechanism of presenilin-1 function: Sensitive gate dynamics and loop unplugging control protein access 2016-02-04
  2. Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease 2007-11-01

Studies

2 studies carry this tag.

Date range

2007 to 2016

Top journals

  • Neurobiology of disease 1
  • The Journal of neuroscience : the official journal of the Society for Neuroscience 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. The dynamic mechanism of presenilin-1 function: Sensitive gate dynamics and loop unplugging control protein access

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of disease 2016-02-04 Biomarkers

    There is no molecular explanation for the many presenilin 1 (PSEN1) mutations causing Alzheimer's disease, but both gain of function relating to amyloid production and loss of isolated PSEN1 function have been implied.

  2. Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2007-11-01 Biomarkers

    Mutations in the PSEN1 gene encoding presenilin 1 (PS1) are linked to a vast majority of pedigrees with early-onset, autosomal dominant forms of familial Alzheimer's disease (FAD).

All topic tags with their study counts