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polymorphism
5 studies tagged polymorphism, dated 1999-01-01 to 2016-02-26. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci 2016-02-26
- Hypovitaminosis D3, Leukopenia, and Human Serotonin Transporter Polymorphism in Anorexia Nervosa and Bulimia Nervosa 2016-01-24
- A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease 2009-12-22
Studies
5 studies carry this tag.
Date range
1999 to 2016
Top journals
- Experimental neurology 1
- Mediators of inflammation 1
- PloS one 1
- The Journal of neuroscience : the official journal of the Society for Neuroscience 1
- The pharmacogenomics journal 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Late onset Alzheimer's disease (LOAD) is a genetically complex and clinically heterogeneous disease.
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Vitamin D3 has been described to have different extraskeletal roles by acting as parahormone in obesity, diabetes, cancer, cognitive impairment, and dementia and to have important regulatory functions in innate immunity.
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The ɛ4 allele of the apolipoprotein E (APOE) gene is currently the strongest and most highly replicated genetic factor for risk and age of onset of late-onset Alzheimer's disease (LOAD).
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Inheritance of the apoE4 allele (epsilon4) increases the risk of developing Alzheimer's disease; however, the mechanisms underlying this association remain elusive.
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Myeloperoxidase (MPO) is a myeloid-specific enzyme that generates hypochlorous acid and other reactive oxygen species.