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plasma-ptau217
4 studies tagged plasma-ptau217, dated 2024-01-05 to 2025-08-06. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Potential utility of plasma pTau217 for assessing amyloid and tau biomarker profiles 2025-08-06
- Plasma pTau217 ratio predicts continuous regional brain tau accumulation in amyloid-positive early Alzheimer's disease 2024-11-22
- Plasma pTau217 predicts continuous brain amyloid levels in preclinical and early Alzheimer's disease 2024-06-28
Studies
4 studies carry this tag.
Date range
2024 to 2025
Top journals
- Alzheimer's & dementia : the journal of the Alzheimer's Association 2
- European journal of nuclear medicine and molecular imaging 1
- Scientific reports 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Plasma pTau217 is effective for predicting A/T biomarker profile and cognitive decline, though further study is needed to better explain its association with Aβ and tau PET staging.
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PTau217R reliably predicts regional tau accumulation in early AD, reducing reliance on tau PET scans and broadening its clinical application.
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55/100
Models integrating pTau217R outperformed Aβ42/Aβ40 alone, predicting amyloid levels up to 89.1 CL.
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A growing literature suggests that plasma levels of tau phosphorylated at amino acid 217 (pTau217) performs similarly to cerebrospinal fluid (CSF) biomarkers and PET imaging to detect amyloid pathology and to provide diagnostic and prognostic information in Alzheimer's disease (AD), but a significant limiting factor thus far has been a lack of widely available immunoassays.