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plasma-biomarkers
12 studies tagged plasma-biomarkers, dated 2013-12-07 to 2025-08-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Profiling Plasma Biomarkers, Particularly pTau217 and pTau217/Aβ42, and Their Relation to Cognition in Memory Clinic Patients 2025-08-01
- Cut-points and gray zones: The challenges of integrating Alzheimer's disease plasma biomarkers into clinical practice 2025-03-01
- Cutting through the noise: A narrative review of Alzheimer's disease plasma biomarkers for routine clinical use 2025-01-14
Studies
12 studies carry this tag.
Date range
2013 to 2025
Top journals
- Alzheimer's & dementia : the journal of the Alzheimer's Association 5
- Alzheimer's research & therapy 1
- CPT: pharmacometrics & systems pharmacology 1
- International journal of geriatric psychiatry 1
- Journal of affective disorders 1
8 journals in all.
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Alzheimer's disease (AD) is characterized by brain protein depositions, impaired synaptic transmission, and progressive cognitive decline.
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Plasma biomarkers for Alzheimer's disease (AD), such as plasma phosphorylated (p)-tau217, offer a more accessible means of testing for the presence of AD pathology compared to cerebrospinal fluid (CSF) or positron emission tomography (PET) methods.
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As novel, anti-amyloid therapies have become more widely available, access to timely and accurate diagnosis has become integral to ensuring optimal treatment of patients with early-stage Alzheimer's disease (AD).
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Amyloid, tau, neurodegeneration and neuroinflammation plasma biomarkers are modified in DLB, albeit with moderate diagnosis performance.
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These relatively non-invasive tests may be beneficial for clinical screening after replication in other populations and validation through neuroimaging or cerebrospinal fluid analysis.
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Elevated levels of AD biomarker p-tau181/Aβ42, by itself or combined with a low Aβ42/Aβ40 level, predicts clinically diagnosed AD.
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60/100
This study supported neuropsychiatric symptoms as early manifestations of preclinical Alzheimer's disease, and suggested plasma NfL to be a potential biomarker for detecting neuropsychiatric symptoms in Alzheimer's continuum.
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GFAP, NfL, and p-tau181 are valuable predictors of cognition and function across common neurodegenerative diseases, and may be useful in specialized clinics and clinical trials.
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This study supports that PET- and CSF-related A/T/N profiles can be used to predict accurately the stages of AD neuropathology.
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Lecanemab is a humanized immunoglobulin G1 monoclonal antibody that selectively binds to soluble Aβ aggregate species, while demonstrating low affinity for Aβ monomer.
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Brain degeneration in patients with Alzheimer's disease (AD) results from the accumulation of pathological amyloid- (Aβ) plaques and tau protein tangles, leading to altered plasma levels of biomarkers.
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The plasma Aβ40 biomarker was able to distinguish between AD and NC groups.