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Home › Research › Topics › peptide

peptide

11 studies tagged peptide, dated 1993-11-01 to 2024-06-01. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Amino-terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4 and deposit in a subset of Alzheimer's disease brains 2024-06-01
  2. Identification of the Aβ37/42 peptide ratio in CSF as an improved Aβ biomarker for Alzheimer's disease 2022-03-12
  3. Early detection of Alzheimer's disease by peptides from phage display screening 2019-06-24

Studies

11 studies carry this tag.

Date range

1993 to 2024

Top journals

  • Journal of neurochemistry 2
  • Alzheimer's & dementia : the journal of the Alzheimer's Association 1
  • Brain research 1
  • Cell reports 1
  • Chemico-biological interactions 1

10 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Amino-terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4 and deposit in a subset of Alzheimer's disease brains

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Neuropathology and applied neurobiology 2024-06-01 Biomarkers

    The current findings implicate ADAMTS4 in both the pathological process of Aβ peptide aggregation and in the early detection of amyloid pathology in AD.

  2. Identification of the Aβ37/42 peptide ratio in CSF as an improved Aβ biomarker for Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2022-03-12 Biomarkers

    We conclude that the Aβ 37/42 ratio sensitively detects presenilin/γ-secretase dysfunction and better distinguishes CN from AD than Aβ42/40 in CSF.

  3. Early detection of Alzheimer's disease by peptides from phage display screening

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Brain research 2019-06-24 Biomarkers

    Alzheimer's disease (AD) is the most common neurodegenerative disorder without effective treatment so far.

  4. The Alzheimer's Disease γ-Secretase Generates Higher 42:40 Ratios for β-Amyloid Than for p3 Peptides

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Cell reports 2017-06-01 Biomarkers

    Alzheimer's disease is characterized by intracerebral deposition of β-amyloid (Aβ).

  5. Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neurobiology of aging 2015-06-19 Biomarkers

    We examined the contribution of candidates genes for Alzheimer's disease (AD) to individual differences in levels of beta amyloid peptides in adults with Down syndrom, a population at high risk for AD.

  6. Roles of serum fibrinogen α chain-derived peptides in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. International journal of geriatric psychiatry 2013-11-05 Biomarkers

    The profile of 10 FIBA-derived peptides combined with age would be a candidate biomarker for AD, which facilitates screening of the disease.

  7. Discovering and targeting the basic mechanism of neurodegeneration: the role of peptides from the C-terminus of acetylcholinesterase: non-hydrolytic effects of ache: the actions of peptides derived from the C-terminal and their relevance to neurodegeneration

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Chemico-biological interactions 2013-04-03 Biomarkers

    Acetylcholinesterase (AChE) is now well-established widely as a signalling molecule with non-hydrolytic functions including trophic activity in a diverse variety of situations in both neural and non-neural tissues.

  8. Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of neurochemistry 2007-01-24 Tau biomarkers

    Neurochemical dementia diagnostics (NDD) can significantly improve the clinically based categorization of patients with early dementia disorders, and the cerebrospinal fluid (CSF) concentrations of amyloid beta peptides ending at the amino acid position of 42 (A beta x-42 and A beta 1-42) are widely accepted biomarkers of Alzheimer's disease (AD).

  9. Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma

    ✓ Peer-reviewed alzhub usefulness score 43 out of 100. The Journal of biological chemistry 1996-12-01 Tau biomarkers

    The amyloid beta-peptide (Abeta) is the major constituent of neuritic plaques in Alzheimer's disease and occurs as a soluble 40-42-residue peptide in cerebrospinal fluid and blood of both normal and AD subjects.

  10. Amyloid beta peptide of Alzheimer's disease downregulates Bcl-2 and upregulates bax expression in human neurons

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 1996-12-01 Tau biomarkers

    Neuronal apoptosis is a suspected cause of neurodegeneration in Alzheimer's disease (AD).

  11. Characterization of beta-amyloid peptide from human cerebrospinal fluid

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of neurochemistry 1993-11-01 Tau biomarkers

    beta-Amyloid peptide (A beta) is one of the main components of senile plaques in the brain tissue of Alzheimer's disease (AD) patients.

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