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mouse-brain
5 studies tagged mouse-brain, dated 2010-06-25 to 2020-09-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome 2020-09-01
- Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain 2018-05-17
- Extracellular Mitochondria and Mitochondrial Components Act as Damage-Associated Molecular Pattern Molecules in the Mouse Brain 2016-08-25
Studies
5 studies carry this tag.
Date range
2010 to 2020
Top journals
- Cell reports 1
- Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 1
- Neurobiology of aging 1
- Neuron 1
- Proceedings of the National Academy of Sciences of the United States of America 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Gene and protein expression data provide useful resources for understanding brain function, but little is known about the lipid composition of the brain.
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Rare heterozygous coding variants in the triggering receptor expressed in myeloid cells 2 (TREM2) gene, conferring increased risk of developing late-onset Alzheimer's disease, have been identified.
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Mitochondria and mitochondrial debris are found in the brain's extracellular space, and extracellular mitochondrial components can act as damage associated molecular pattern (DAMP) molecules.
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We recently reported that homozygous Presenilin-1 (Psen1) knockin (KI) mice carrying the familial Alzheimer's disease (FAD) mutation L435F or C410Y recapitulate the phenotypes of Psen1(-/-) mice.
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Because mouse models play a crucial role in biomedical research related to the human nervous system, understanding the similarities and differences between mouse and human brain is of fundamental importance.