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Newest in this topic

  1. Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome 2020-09-01
  2. Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain 2018-05-17
  3. Extracellular Mitochondria and Mitochondrial Components Act as Damage-Associated Molecular Pattern Molecules in the Mouse Brain 2016-08-25

Studies

5 studies carry this tag.

Date range

2010 to 2020

Top journals

  • Cell reports 1
  • Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 1
  • Neurobiology of aging 1
  • Neuron 1
  • Proceedings of the National Academy of Sciences of the United States of America 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Cell reports 2020-09-01 Genetics

    Gene and protein expression data provide useful resources for understanding brain function, but little is known about the lipid composition of the brain.

  2. Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Neurobiology of aging 2018-05-17 TREM2 and immune genetics

    Rare heterozygous coding variants in the triggering receptor expressed in myeloid cells 2 (TREM2) gene, conferring increased risk of developing late-onset Alzheimer's disease, have been identified.

  3. Extracellular Mitochondria and Mitochondrial Components Act as Damage-Associated Molecular Pattern Molecules in the Mouse Brain

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2016-08-25 TREM2 and immune genetics

    Mitochondria and mitochondrial debris are found in the brain's extracellular space, and extracellular mitochondrial components can act as damage associated molecular pattern (DAMP) molecules.

  4. Loss of Aβ43 Production Caused by Presenilin-1 Mutations in the Knockin Mouse Brain

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuron 2016-04-01 Biomarkers

    We recently reported that homozygous Presenilin-1 (Psen1) knockin (KI) mice carrying the familial Alzheimer's disease (FAD) mutation L435F or C410Y recapitulate the phenotypes of Psen1(-/-) mice.

  5. Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2010-06-25 Risk genes beyond APOE

    Because mouse models play a crucial role in biomedical research related to the human nervous system, understanding the similarities and differences between mouse and human brain is of fundamental importance.

All topic tags with their study counts