Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest in this topic

  1. White matter free water mediates the associations between placental growth factor, white matter hyperintensities, and cognitive status 2024-12-18
  2. Tau seeds from Alzheimer's disease brains trigger tau spread in macaques while oligomeric-Aβ mediates pathology maturation 2023-12-26
  3. The Microglial membrane receptor TREM2 mediates exosome secretion to promote phagocytosis of amyloid-β by microglia 2022-03-23

Studies

5 studies carry this tag.

Date range

2016 to 2024

Top journals

  • Alzheimer's & dementia : the journal of the Alzheimer's Association 2
  • FEBS letters 1
  • Journal of Alzheimer's disease : JAD 1
  • Proceedings of the National Academy of Sciences of the United States of America 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. White matter free water mediates the associations between placental growth factor, white matter hyperintensities, and cognitive status

    ✓ Peer-reviewed alzhub usefulness score 57 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2024-12-18 Biomarkers

    Elevated PlGF may contribute to WMH and cognitive impairment through white matter FW accumulation.

  2. Tau seeds from Alzheimer's disease brains trigger tau spread in macaques while oligomeric-Aβ mediates pathology maturation

    ✓ Peer-reviewed alzhub usefulness score 48 out of 100. Alzheimer's & dementia : the journal of the Alzheimer's Association 2023-12-26 Biomarkers

    Oligomeric-Aβ mediates the maturation of tau pathology and its neuronal toxicity in macaques but not its initial spreading.

  3. The Microglial membrane receptor TREM2 mediates exosome secretion to promote phagocytosis of amyloid-β by microglia

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. FEBS letters 2022-03-23 TREM2 and immune genetics

    Considerable evidence links the microglial transmembrane receptor TREM2 to the progression of Alzheimer's disease through its involvement in Aβ phagocytosis by microglia.

  4. RIPK1 mediates a disease-associated microglial response in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2017-09-13 Risk genes beyond APOE

    Dysfunction of microglia is known to play an important role in Alzheimer's disease (AD).

  5. ABCA7 Mediates Phagocytic Clearance of Amyloid-β in the Brain

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Alzheimer's disease : JAD 2016-09-01 Genetics

    Alzheimer's disease (AD) is a neurodegenerative disorder characterized by dementia and abnormal deposits of aggregated amyloid-β in the brain.

All topic tags with their study counts