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link
3 studies tagged link, dated 2016-03-31 to 2025-02-12. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Soluble cerebral Aβ protofibrils link Aβ plaque pathology to changes in CSF Aβ42/Aβ40 ratios, neurofilament light and tau in Alzheimer's disease model mice 2025-02-12
- Peripheral innate immunophenotype in neurodegenerative disease: blood-based profiles and links to survival 2024-10-29
- Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta 2016-03-31
Studies
3 studies carry this tag.
Date range
2016 to 2025
Top journals
- BMC biology 1
- Molecular psychiatry 1
- Nature aging 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The Aβ 42 /Aβ 40 ratio in the cerebrospinal fluid (CSF) and the concentrations of neurofilament light (NfL) and total tau (t-tau) are changed in the early stages of Alzheimer's disease (AD) 1 , but their neurobiological correlates are not entirely understood.
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The innate immune system plays an integral role in the progression of many neurodegenerative diseases.
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Our findings identify Syt1 as a novel Ca(2+)-sensitive PS1 modulator that could regulate synaptic Aβ, opening avenues for novel and selective synapse targeting therapeutic strategies.