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Home › Research › Topics › insulin-receptor

insulin-receptor

3 studies tagged insulin-receptor, dated 2011-01-13 to 2017-09-01. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes 2017-09-01
  2. Intranasal Insulin Administration Ameliorates Streptozotocin (ICV)-Induced Insulin Receptor Dysfunction, Neuroinflammation, Amyloidogenesis, and Memory Impairment in Rats 2016-10-11
  3. Effect of glycogen synthase kinase 3 β-mediated presenilin 1 phosphorylation on amyloid β production is negatively regulated by insulin receptor cleavage 2011-01-13

Studies

3 studies carry this tag.

Date range

2011 to 2017

Top journals

  • Molecular neurobiology 1
  • Neuron 1
  • Neuroscience 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Neuron 2017-09-01 Genetics

    Diabetes and impaired brain insulin signaling are linked to the pathogenesis of Alzheimer's disease (AD).

  2. Intranasal Insulin Administration Ameliorates Streptozotocin (ICV)-Induced Insulin Receptor Dysfunction, Neuroinflammation, Amyloidogenesis, and Memory Impairment in Rats

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Molecular neurobiology 2016-10-11 Biomarkers

    Alzheimer's disease (AD) is associated with reduced insulin level and impairment of insulin receptor (IR) signaling in the brain, which correlates to amyloid pathology, neuroinflammation, and synaptic neurotoxicity.

  3. Effect of glycogen synthase kinase 3 β-mediated presenilin 1 phosphorylation on amyloid β production is negatively regulated by insulin receptor cleavage

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuroscience 2011-01-13 Biomarkers

    Presenilin 1 (PS1), a causative molecule of familial Alzheimer's disease (AD), is known to be an unprimed substrate of glycogen synthase kinase 3 β (GSK3β) [Twomey and McCarthy (2006) FEBS Lett 580:4015-4020] and is phosphorylated at serine 353, 357 residues in its cytoplasmic loop region [Kirschenbaum et al. (2001) J Biol Chem 276:7366-7375].

All topic tags with their study counts