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inhibition
5 studies tagged inhibition, dated 2012-07-02 to 2023-11-29. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Inhibition of asparagine endopeptidase (AEP) effectively treats sporadic Alzheimer's disease in mice 2023-11-29
- Forsythoside B attenuates memory impairment and neuroinflammation via inhibition on NF-κB signaling in Alzheimer's disease 2020-10-15
- Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer's disease mouse model 2019-12-04
Studies
5 studies carry this tag.
Date range
2012 to 2023
Top journals
- Journal of neuroinflammation 2
- Aging 1
- Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 1
- Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Alzheimer's disease (AD) is a progressive neurodegenerative disease with cognitive dysfunction as its major clinical symptom.
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FTS•B effectively counteracted cognitive decline by regulating neuroinflammation via NF-κB signaling in APP/PS1 mice, providing preliminary experimental evidence that FTS•B is a promising therapeutic agent in AD treatment.
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The implication of epigenetic mechanisms in Alzheimer's disease (AD) has been demonstrated in several studies.
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Although plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) protects against cerebral ischemia and spinal cord injury-induced oxidative stress and inflammation by activating the nuclear factor-erythroid 2-related factor-2 /antioxidant response element (Nrf2/ARE) pathway, its role in the amelioration of neurodegenerative diseases remains unexplored.
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These data suggest that amyloid dependent microgliosis may be Src kinase dependent in vitro and in vivo.