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Newest in this topic

  1. Inhibition of asparagine endopeptidase (AEP) effectively treats sporadic Alzheimer's disease in mice 2023-11-29
  2. Forsythoside B attenuates memory impairment and neuroinflammation via inhibition on NF-κB signaling in Alzheimer's disease 2020-10-15
  3. Pharmacological inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer's disease mouse model 2019-12-04

Studies

5 studies carry this tag.

Date range

2012 to 2023

Top journals

  • Journal of neuroinflammation 2
  • Aging 1
  • Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 1
  • Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Inhibition of asparagine endopeptidase (AEP) effectively treats sporadic Alzheimer's disease in mice

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2023-11-29 Biomarkers

    Alzheimer's disease (AD) is a progressive neurodegenerative disease with cognitive dysfunction as its major clinical symptom.

  2. Forsythoside B attenuates memory impairment and neuroinflammation via inhibition on NF-κB signaling in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Journal of neuroinflammation 2020-10-15 Biomarkers

    FTS•B effectively counteracted cognitive decline by regulating neuroinflammation via NF-κB signaling in APP/PS1 mice, providing preliminary experimental evidence that FTS•B is a promising therapeutic agent in AD treatment.

  3. The implication of epigenetic mechanisms in Alzheimer's disease (AD) has been demonstrated in several studies.

  4. Plumbagin ameliorates memory dysfunction in streptozotocin induced Alzheimer's disease via activation of Nrf2/ARE pathway and inhibition of β-secretase

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018-03-22 Biomarkers

    Although plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) protects against cerebral ischemia and spinal cord injury-induced oxidative stress and inflammation by activating the nuclear factor-erythroid 2-related factor-2 /antioxidant response element (Nrf2/ARE) pathway, its role in the amelioration of neurodegenerative diseases remains unexplored.

  5. Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Journal of neuroinflammation 2012-07-02 Biomarkers

    These data suggest that amyloid dependent microgliosis may be Src kinase dependent in vitro and in vivo.

All topic tags with their study counts