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independent
4 studies tagged independent, dated 2018-01-01 to 2024-02-07. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Fully automated measurement of plasma Aβ42/40 and p-tau181: Analytical robustness and concordance with cerebrospinal fluid profile along the Alzheimer's disease continuum in two independent cohorts 2024-02-07
- Independent study demonstrates amyloid probability score accurately indicates amyloid pathology 2023-03-28
- Age, sex and APOE-ε4 modify the balance between soluble and fibrillar β-amyloid in non-demented individuals: topographical patterns across two independent cohorts 2022-03-02
Studies
4 studies carry this tag.
Date range
2018 to 2024
Top journals
- Alzheimer's & dementia : the journal of the Alzheimer's Association 1
- Annals of clinical and translational neurology 1
- Journal of Alzheimer's disease : JAD 1
- Molecular psychiatry 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The identified cutoffs and probability-based models represent a significant step toward plasma AD molecular diagnosis.
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57/100
The study shows individuals with a high APS are more likely than those with a low APS to have abnormal amounts of amyloid plaques and be on an amyloid accumulation trajectory, a dynamic and evolving process characteristic of progressive AD pathology.
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Amyloid (Aβ) pathology is the earliest detectable pathophysiological event along the Alzheimer's continuum, which can be measured both in the cerebrospinal fluid (CSF) and by Positron Emission Tomography (PET).
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This study confirms strong concordance between CSF biomarkers and PET Aβ-amyloid status is independent of immunoassay platform, supporting their utility as biomarkers in clinical practice for the diagnosis of AD and for participant enrichment in clinical trials.