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Newest in this topic

  1. Increased expression of the frontotemporal dementia risk factor TMEM106B causes C9orf72-dependent alterations in lysosomes 2016-04-28
  2. Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease 2002-06-01

Studies

2 studies carry this tag.

Date range

2002 to 2016

Top journals

  • Annals of neurology 1
  • Human molecular genetics 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Increased expression of the frontotemporal dementia risk factor TMEM106B causes C9orf72-dependent alterations in lysosomes

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Human molecular genetics 2016-04-28 Genetics

    Frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) is an important cause of dementia in individuals under age 65.

  2. Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Annals of neurology 2002-06-01 Risk genes beyond APOE

    Beta-secretase cleavage represents the first step in the generation of Abeta polypeptides and initiates the amyloid cascade that leads to neurodegeneration in Alzheimer's disease.

All topic tags with their study counts