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Home › Research › Topics › fragments

fragments

3 studies tagged fragments, dated 2001-07-10 to 2013-05-22. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. An enzyme-generated fragment of tau measured in serum shows an inverse correlation to cognitive function 2013-05-22
  2. Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity 2005-12-12
  3. Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons 2001-07-10

Studies

3 studies carry this tag.

Date range

2001 to 2013

Top journals

  • Proceedings of the National Academy of Sciences of the United States of America 2
  • PloS one 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. An enzyme-generated fragment of tau measured in serum shows an inverse correlation to cognitive function

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. PloS one 2013-05-22 Biomarkers

    Based on the hypothesis that tau is cleaved proteolytically and then released into the blood, we here provide evidence for the presence of an ADAM10-generated tau fragment (Tau-A) in serum.

  2. Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2005-12-12 Genetics

    Apolipoprotein (apo) E4, a 299-aa protein and a major risk factor for Alzheimer's disease, can be cleaved to generate C-terminal-truncated fragments that cause neurotoxicity in vitro and neurodegeneration and behavioral deficits in transgenic mice.

  3. Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2001-07-10 Genetics

    Human apolipoprotein (apo) E4, a major risk factor for Alzheimer's disease (AD), occurs in amyloid plaques and neurofibrillary tangles (NFTs) in AD brains; however, its role in the pathogenesis of these lesions is unclear.

All topic tags with their study counts