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Newest in this topic

  1. Retrograde transport of γ-secretase from endosomes to the trans-Golgi network regulates Aβ42 production 2018-08-16
  2. Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes 2017-09-01

Studies

2 studies carry this tag.

Date range

2017 to 2018

Top journals

  • Journal of neurochemistry 1
  • Neuron 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Retrograde transport of γ-secretase from endosomes to the trans-Golgi network regulates Aβ42 production

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Journal of neurochemistry 2018-08-16 Biomarkers

    The aberrant metabolism of amyloid-β protein (Aβ) in the human brain has been implicated in the etiology of Alzheimer disease (AD). γ-Secretase is the enzyme that generates various forms of Aβ, such as Aβ40 and Aβ42, the latter being an aggregation-prone toxic peptide that is involved in the pathogenesis of AD.

  2. Apolipoprotein E4 Impairs Neuronal Insulin Signaling by Trapping Insulin Receptor in the Endosomes

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Neuron 2017-09-01 Genetics

    Diabetes and impaired brain insulin signaling are linked to the pathogenesis of Alzheimer's disease (AD).

All topic tags with their study counts