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drosophila
4 studies tagged drosophila, dated 1999-04-01 to 2018-03-29. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models 2018-03-29
- Functional screening of Alzheimer pathology genome-wide association signals in Drosophila 2011-02-03
- Alzheimer's disease: insights from Drosophila melanogaster models 2009-12-25
Studies
4 studies carry this tag.
Date range
1999 to 2018
Top journals
- American journal of human genetics 1
- Genome medicine 1
- Nature 1
- Trends in biochemical sciences 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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The comprehensive pathological and molecular data generated through this study strongly validate the causal role of TREM2/TYROBP in driving molecular networks in AD and AD-related phenotypes in flies.
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We have leveraged a Drosophila model relevant to Alzheimer disease (AD) for functional screening of findings from a genome-wide scan for loci associated with a quantitative measure of AD pathology in humans.
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The power of fruit fly genetics is being deployed against some of the most intractable and economically significant problems in modern medicine, the neurodegenerative diseases.
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Presenilin proteins have been implicated both in developmental signalling by the cell-surface protein Notch and in the pathogenesis of Alzheimer's disease.