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Newest in this topic

  1. Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models 2018-03-29
  2. Functional screening of Alzheimer pathology genome-wide association signals in Drosophila 2011-02-03
  3. Alzheimer's disease: insights from Drosophila melanogaster models 2009-12-25

Studies

4 studies carry this tag.

Date range

1999 to 2018

Top journals

  • American journal of human genetics 1
  • Genome medicine 1
  • Nature 1
  • Trends in biochemical sciences 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Genome medicine 2018-03-29 TREM2 and immune genetics

    The comprehensive pathological and molecular data generated through this study strongly validate the causal role of TREM2/TYROBP in driving molecular networks in AD and AD-related phenotypes in flies.

  2. Functional screening of Alzheimer pathology genome-wide association signals in Drosophila

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. American journal of human genetics 2011-02-03 Genetics

    We have leveraged a Drosophila model relevant to Alzheimer disease (AD) for functional screening of findings from a genome-wide scan for loci associated with a quantitative measure of AD pathology in humans.

  3. Alzheimer's disease: insights from Drosophila melanogaster models

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Trends in biochemical sciences 2009-12-25 Genetics

    The power of fruit fly genetics is being deployed against some of the most intractable and economically significant problems in modern medicine, the neurodegenerative diseases.

  4. Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Nature 1999-04-01 Risk genes beyond APOE

    Presenilin proteins have been implicated both in developmental signalling by the cell-surface protein Notch and in the pathogenesis of Alzheimer's disease.

All topic tags with their study counts