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disease-like
3 studies tagged disease-like, dated 2016-01-12 to 2022-09-16. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Fusobacterium nucleatum infection-induced neurodegeneration and abnormal gut microbiota composition in Alzheimer's disease-like rats 2022-09-16
- New Insights into the Spontaneous Human Alzheimer's Disease-Like Model Octodon degus: Unraveling Amyloid-β Peptide Aggregation and Age-Related Amyloid Pathology 2018-01-01
- Alzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression 2016-01-12
Studies
3 studies carry this tag.
Date range
2016 to 2022
Top journals
- Frontiers in neuroscience 1
- Journal of Alzheimer's disease : JAD 1
- Molecular neurodegeneration 1
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Oral infection with F. nucleatum could contribute to abnormalities in cognitive ability and pathological change in the brain of AD-like rats, which may be related to abnormal gut microbiota composition.
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Alzheimer's disease (AD) is the most common cause of dementia worldwide.
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This demonstrates that an AD-like APP processing, yielding to levels of APP, βCTF and Aβ42/Aβ40 ratio similar to those observed in AD patients, are sufficient to rapidly trigger early steps of the amyloidogenic and Tau pathways in vivo.