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Home › Research › Topics › disease-associated

disease-associated

5 studies tagged disease-associated, dated 2016-08-03 to 2021-02-04. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Deletion of Alzheimer's disease-associated CD33 results in an inflammatory human microglia phenotype 2021-02-04
  2. PU.1 regulates Alzheimer's disease-associated genes in primary human microglia 2018-08-20
  3. RIPK1 mediates a disease-associated microglial response in Alzheimer's disease 2017-09-13

Studies

5 studies carry this tag.

Date range

2016 to 2021

Top journals

  • Molecular neurodegeneration 2
  • Frontiers in neuroscience 1
  • Glia 1
  • Proceedings of the National Academy of Sciences of the United States of America 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Deletion of Alzheimer's disease-associated CD33 results in an inflammatory human microglia phenotype

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Glia 2021-02-04 Genetics

    Genome-wide association studies demonstrated that polymorphisms in the CD33/sialic acid-binding immunoglobulin-like lectin 3 gene are associated with late-onset Alzheimer's disease (AD).

  2. PU.1 regulates Alzheimer's disease-associated genes in primary human microglia

    ✓ Peer-reviewed alzhub usefulness score 41 out of 100. Molecular neurodegeneration 2018-08-20 Genetics

    In the brain, PU.1 is specifically expressed in microglia and recent evidence from genome-wide association studies suggests that reductions in PU.1 contribute to a delayed onset of Alzheimer's disease (AD), possibly through limiting neuroinflammatory responses.

  3. RIPK1 mediates a disease-associated microglial response in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 38 out of 100. Proceedings of the National Academy of Sciences of the United States of America 2017-09-13 Risk genes beyond APOE

    Dysfunction of microglia is known to play an important role in Alzheimer's disease (AD).

  4. The Alzheimer's Disease-Associated R47H Variant of TREM2 Has an Altered Glycosylation Pattern and Protein Stability

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Frontiers in neuroscience 2017-01-18 TREM2 and immune genetics

    The R47H coding variant of the triggering receptor expressed on myeloid cells-2 (TREM2) increases the risk of Alzheimer's disease (AD) similar to apolipoprotein E4.

  5. Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Molecular neurodegeneration 2016-08-03 Genetics

    Our study provides new insights into the brain distribution and cellular expression of an important risk factor associated with late-onset AD.

All topic tags with their study counts