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Home › Research › Topics › degeneration

degeneration

6 studies tagged degeneration, dated 1997-01-01 to 2020-01-08. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. Longitudinal Basal Forebrain Degeneration Interacts with TREM2/C3 Biomarkers of Inflammation in Presymptomatic Alzheimer's Disease 2020-01-08
  2. Kraepelin revisited: schizophrenia from degeneration to failed regeneration 2015-03-31
  3. SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease 2014-11-23

Studies

6 studies carry this tag.

Date range

1997 to 2020

Top journals

  • Annual review of neuroscience 1
  • Japanese journal of pharmacology 1
  • Molecular neurodegeneration 1
  • Molecular psychiatry 1
  • Neuron 1

6 journals in all.

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. Longitudinal Basal Forebrain Degeneration Interacts with TREM2/C3 Biomarkers of Inflammation in Presymptomatic Alzheimer's Disease

    ✓ Peer-reviewed alzhub usefulness score 53 out of 100. The Journal of neuroscience : the official journal of the Society for Neuroscience 2020-01-08 TREM2 and immune genetics

    Longitudinal loss of basal forebrain volume was larger in the preclinical compared with the neurotypical subgroup.

  2. Kraepelin revisited: schizophrenia from degeneration to failed regeneration

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Molecular psychiatry 2015-03-31 Genetics

    One hundred years after its conceptual definition as 'Dementia Praecox' by Emil Kraepelin, schizophrenia is still a serious psychiatric illness that affects young adults and leads to disability in at least half of patients.

  3. SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Molecular neurodegeneration 2014-11-23 Tau biomarkers

    We developed a sensitive method to analyze SNAP-25 levels in individual CSF samples that to our knowledge was not possible previously.

  4. Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Neuron 2006-07-01 Risk genes beyond APOE

    Degeneration of basal forebrain cholinergic neurons (BFCNs) contributes to cognitive dysfunction in Alzheimer's disease (AD) and Down's syndrome (DS).

  5. Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Annual review of neuroscience 2003-04-18 Risk genes beyond APOE

    Intensive studies of three proteins--Presenilin, Notch, and the amyloid precursor protein (APP)--have led to the recognition of a direct intersection between early development and late-life neurodegeneration.

  6. Continuous infusion of beta-amyloid protein into the rat cerebral ventricle induces learning impairment and neuronal and morphological degeneration

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Japanese journal of pharmacology 1997-01-01 Biomarkers

    To investigate the toxicity of beta-amyloid protein, a component of the senile plaques in Alzheimer's disease, it was infused into the cerebral ventricle of rats for 14 days by a mini-osmotic pump.

All topic tags with their study counts