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cycle
2 studies tagged cycle, dated 2019-06-28 to 2021-03-18. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Using rapid cycle tests of change to develop the Carers Assistive Technology Experience Questionnaire: a cognitive interview study in the UK 2021-03-18
- MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration 2019-06-28
Studies
2 studies carry this tag.
Date range
2019 to 2021
Top journals
- Autophagy 1
- BMJ open 1
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We describe the use of rapid cycle tests of change to pretest and develop a Carers Assistive Technology Experience Questionnaire for a survey of informal carers of persons with dementia.
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Here, we found that overexpression of human wild-type full-length MAPT, which models MAPT pathologies as seen in sporadic AD patients, induced autophagy deficits via repression of autophagosome-lysosome fusion leading to significantly increased LC3 (microtubule-associated protein 1 light chain 3)-II and SQSTM1/p62 (sequestosome 1) protein levels with autophagosome accumulation.