alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Home › Research › Topics › copy-number

copy-number

4 studies tagged copy-number, dated 2010-01-01 to 2022-01-13. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia 2022-01-13
  2. Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains 2017-02-02
  3. Mitochondrial DNA copy numbers in pyramidal neurons are decreased and mitochondrial biogenesis transcriptome signaling is disrupted in Alzheimer's disease hippocampi 2014-01-01

Studies

4 studies carry this tag.

Date range

2010 to 2022

Top journals

  • Journal of Alzheimer's disease : JAD 2
  • Acta neuropathologica communications 1
  • eLife 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. eLife 2022-01-13 Genetics

    Our genetic findings indicate that mtDNA-CN is a complex biomarker reflecting specific MT processes related to mtDNA regulation, and that these processes are causally related to human diseases.

  2. Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains

    ✓ Peer-reviewed alzhub usefulness score 55 out of 100. Acta neuropathologica communications 2017-02-02 Genetics

    Mitochondria play a key role in common neurodegenerative diseases and contain their own genome: mtDNA.

  3. Mitochondrial DNA copy numbers in pyramidal neurons are decreased and mitochondrial biogenesis transcriptome signaling is disrupted in Alzheimer's disease hippocampi

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Alzheimer's disease : JAD 2014-01-01 Biomarkers

    Alzheimer's disease (AD) is the major cause of adult-onset dementia and is characterized in its pre-diagnostic stage by reduced cerebral cortical glucose metabolism and in later stages by reduced cortical oxygen uptake, implying reduced mitochondrial respiration.

  4. Genome-wide scan of copy number variation in late-onset Alzheimer's disease

    ✓ Peer-reviewed alzhub usefulness score 36 out of 100. Journal of Alzheimer's disease : JAD 2010-01-01 Genetics

    Alzheimer's disease is a complex and progressive neurodegenerative disease leading to loss of memory, cognitive impairment, and ultimately death.

All topic tags with their study counts