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Home › Research › Topics › conformation

conformation

3 studies tagged conformation, dated 2011-02-10 to 2020-12-26. Bibliography: BibTeX (.bib) · RIS (.ris)

Newest in this topic

  1. A Conformation Variant of p53 Combined with Machine Learning Identifies Alzheimer Disease in Preclinical and Prodromal Stages 2020-12-26
  2. Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations 2014-04-24
  3. Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation 2011-02-10

Studies

3 studies carry this tag.

Date range

2011 to 2020

Top journals

  • FEBS open bio 1
  • Journal of personalized medicine 1
  • Molecular neurodegeneration 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. A Conformation Variant of p53 Combined with Machine Learning Identifies Alzheimer Disease in Preclinical and Prodromal Stages

    ✓ Peer-reviewed alzhub usefulness score 62 out of 100. Journal of personalized medicine 2020-12-26 Biomarkers

    Early diagnosis of Alzheimer's disease (AD) is a crucial starting point in disease management.

  2. Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. FEBS open bio 2014-04-24 Biomarkers

    The enzyme complex γ-secretase generates amyloid β-peptide (Aβ), a 37-43-residue peptide associated with Alzheimer disease (AD).

  3. Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation

    ✓ Peer-reviewed alzhub usefulness score 40 out of 100. Molecular neurodegeneration 2011-02-10 Biomarkers

    We propose that there is a reciprocal relationship between APP-CT positioning relative to the membrane and PS1 conformation, suggesting that factors that modulate either APP positioning in the membrane or PS1 conformation could be exploited therapeutically.

All topic tags with their study counts