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clinical
3 studies tagged clinical, dated 2017-01-01 to 2025-05-20. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Rapamycin treatment for Alzheimer's disease and related dementias: a pilot phase 1 clinical trial 2025-05-20
- Different neuroinflammatory profile in amyotrophic lateral sclerosis and frontotemporal dementia is linked to the clinical phase 2018-09-17
- The Clinical Use of Cerebrospinal Fluid Biomarkers for Alzheimer's Disease Diagnosis: The Italian Selfie 2017-01-01
Studies
3 studies carry this tag.
Date range
2017 to 2025
Top journals
- Communications medicine 1
- Journal of Alzheimer's disease : JAD 1
- Journal of neurology, neurosurgery, and psychiatry 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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45/100
Rapamycin is not detectable in the CSF before or after treatment, but several Alzheimer's disease and inflammatory biomarkers increase after treatment.
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Our data indicate that neuroinflammation is linked to the symptomatic phase of ALS/FTD and shows a similar pattern in sporadic and genetic cases.
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Although the use of cerebrospinal fluid (CSF) amyloid β1-42 (Aβ42), tau (T-tau), and phosphorylated tau (p-tau181) gives added diagnostic and prognostic values, the diffusion is still limited in clinical practice and only a restricted number of patients receive an integrated clinico-biological diagnosis.