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clinic-cohort
5 studies tagged clinic-cohort, dated 2023-12-22 to 2025-03-27. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Diagnostic performance of plasma p-tau217 in a memory clinic cohort using the Lumipulse automated platform 2025-03-27
- Accuracy and clinical applicability of plasma tau 181 and 217 for Alzheimer's disease diagnosis in a memory clinic cohort 2025-01-23
- Short-term variability of Alzheimer's disease plasma biomarkers in a mixed memory clinic cohort 2025-01-21
Studies
5 studies carry this tag.
Date range
2023 to 2025
Top journals
- Alzheimer's research & therapy 3
- Journal of neurology 1
- Journal of the neurological sciences 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Plasma p-tau217 shows excellent results for detecting amyloid pathology at brain level in a clinical setting with an AUC of 0.95.
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Plasma tau phosphorylated at threonine 181 (p-tau181) and 217 (p-tau217) have demonstrated high accuracy for Alzheimer's disease (AD) diagnosis, defined by CSF/PET amyloid beta (Aβ) positivity, but most studies have been performed in research cohorts, limiting their generalizability.
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67/100
We found low intra-individual variability, robust to various factors, appropriate to capture individual changes in AD BBMs, while moderate inter-individual variability may give rise to caution in diagnostic contexts.
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69/100
In TAP-TAU, we will investigate the added clinical value of tau-PET in a real-world clinical setting, including memory clinic patients with diagnostic uncertainty after routine work-up.
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We found good-excellent reliability (ICC range 0.86-0.93) for most qLRP parameters. qLRP parameters exhibited limited intra-subject variability and we found no large sources of variability when examining subgroups.