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cleavage
4 studies tagged cleavage, dated 1996-02-01 to 2016-03-11. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Effect of Presenilin Mutations on APP Cleavage; Insights into the Pathogenesis of FAD 2016-03-11
- Amyloid-β production via cleavage of amyloid-β protein precursor is modulated by cell density 2010-01-01
- Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brain 2006-03-01
Studies
4 studies carry this tag.
Date range
1996 to 2016
Top journals
- Frontiers in aging neuroscience 1
- Journal of Alzheimer's disease : JAD 1
- The American journal of pathology 1
- The Journal of biological chemistry 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Alzheimer disease (AD) is characterized by progressive memory loss, reduction in cognitive functions, and damage to the brain.
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Mounting evidence suggests that Alzheimer's disease (AD) is caused by the accumulation of the small peptide, amyloid-β (Aβ), a proteolytic cleavage product of amyloid-β protein precursor (AβPP).
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Recent studies demonstrate roles for activation of caspases and cleavage of cellular proteins within neurons of the Alzheimer's disease (AD) brain.
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Amyloid precursor protein (APP) and cholesterol metabolism are genetically linked to Alzheimer's disease, the latter through apolipoprotein E, a lipid and cholesterol transport protein.