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caused
2 studies tagged caused, dated 2007-11-01 to 2016-04-01. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Loss of Aβ43 Production Caused by Presenilin-1 Mutations in the Knockin Mouse Brain 2016-04-01
- Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease 2007-11-01
Studies
2 studies carry this tag.
Date range
2007 to 2016
Top journals
- Neuron 1
- The Journal of neuroscience : the official journal of the Society for Neuroscience 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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We recently reported that homozygous Presenilin-1 (Psen1) knockin (KI) mice carrying the familial Alzheimer's disease (FAD) mutation L435F or C410Y recapitulate the phenotypes of Psen1(-/-) mice.
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Mutations in the PSEN1 gene encoding presenilin 1 (PS1) are linked to a vast majority of pedigrees with early-onset, autosomal dominant forms of familial Alzheimer's disease (FAD).