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Newest in this topic

  1. Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease 2024-11-11
  2. Exploring the possible causal effects of cardiac blood biomarkers in dementia and cognitive performance: a Mendelian randomization study 2023-05-13
  3. Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits 2022-01-20

Studies

4 studies carry this tag.

Date range

2022 to 2024

Top journals

  • Nature genetics 2
  • GeroScience 1
  • eLife 1

Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.

  1. The integration of quantitative trait loci (QTLs) with disease genome-wide association studies (GWASs) has proven successful in prioritizing candidate genes at disease-associated loci.

  2. Exploring the possible causal effects of cardiac blood biomarkers in dementia and cognitive performance: a Mendelian randomization study

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. GeroScience 2023-05-13 Biomarkers

    Prospective cohort studies have implied associations between blood levels of troponin T, troponin I, NT-proBNP, GDF15, dementia, and cognitive function, without providing evidence favoring possible causality.

  3. Multi-ancestry eQTL meta-analysis of human brain identifies candidate causal variants for brain-related traits

    ✓ Peer-reviewed alzhub usefulness score 71 out of 100. Nature genetics 2022-01-20 Genetics

    While large-scale, genome-wide association studies (GWAS) have identified hundreds of loci associated with brain-related traits, identification of the variants, genes and molecular mechanisms underlying these traits remains challenging.

  4. GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia

    ✓ Peer-reviewed alzhub usefulness score 52 out of 100. eLife 2022-01-13 Genetics

    Our genetic findings indicate that mtDNA-CN is a complex biomarker reflecting specific MT processes related to mtDNA regulation, and that these processes are causally related to human diseases.

All topic tags with their study counts