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biomarkers-profile
5 studies tagged biomarkers-profile, dated 2015-01-01 to 2025-08-06. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Potential utility of plasma pTau217 for assessing amyloid and tau biomarker profiles 2025-08-06
- Prevalence and Clinical Implications of a β-Amyloid-Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease 2023-07-31
- Cognitively unimpaired individuals with a low burden of Aβ pathology have a distinct CSF biomarker profile 2021-07-27
Studies
5 studies carry this tag.
Date range
2015 to 2025
Top journals
- Alzheimer's research & therapy 1
- European journal of nuclear medicine and molecular imaging 1
- JAMA neurology 1
- Journal of Alzheimer's disease : JAD 1
- Neurology 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Plasma pTau217 is effective for predicting A/T biomarker profile and cognitive decline, though further study is needed to better explain its association with Aβ and tau PET staging.
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Longitudinally, no significant differences in rates of worsening were observed between A-T+ and A-T- profiles for cognition or imaging biomarkers.
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There are biologically meaningful Aβ-downstream effects in individuals with a low burden of Aβ pathology, while structural and functional changes are still subtle or absent.
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These findings suggest that a simple blood-based signature not only provides estimates of NAB but also predicts cognitive decline and disease progression, identifying individuals at risk of progressing toward AD at the prodromal and preclinical stages.
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The diagnosis of idiopathic normal pressure hydrocephalus (iNPH) is sometimes complicated by concomitant Alzheimer's disease (AD) pathology.