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abeta
5 studies tagged abeta, dated 2000-12-01 to 2005-04-15. Bibliography: BibTeX (.bib) · RIS (.ris)
Newest in this topic
- Proteomic identification of proteins oxidized by Abeta(1-42) in synaptosomes: implications for Alzheimer's disease 2005-04-15
- Time-dependent reduction in Abeta levels after intracranial LPS administration in APP transgenic mice 2004-11-01
- Intra- and extracellular Abeta and PHF in clinically evaluated cases of Alzheimer's disease 2004-07-01
Studies
5 studies carry this tag.
Date range
2000 to 2005
Top journals
- Acta neuropathologica 1
- Brain research 1
- Experimental neurology 1
- Histology and histopathology 1
- Journal of neurochemistry 1
Newest first, then by address. Each study has a usefulness score out of 100 (rubric version 4.0); tap a score to see what makes it up. Tags were assigned automatically from each study's title and summary. The same studies as a filter in the library.
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Protein oxidation has been implicated in Alzheimer's disease (AD) and can lead to loss of protein function, abnormal protein turnover, interference with cell cycle, imbalance of cellular redox potential, and eventually cell death.
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Inflammation has been argued to play a primary role in the pathogenesis of Alzheimer's disease (AD).
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Temporal cortical sections from postmortem brains of individuals without any dementing condition and with different degrees of severity of Alzheimer's disease (AD) evaluated by the Clinical Dementia Rating scale (CDR 0-CDR 3) were analyzed using immunohistochemical procedures.
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Previously, we found that amyloid beta-protein (Abeta)1-42 exhibits neurotoxicity, while Abeta1-40 serves as an antioxidant molecule by quenching metal ions and inhibiting metal-mediated oxygen radical generation.
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The deposition of the amyloid beta-protein (Abeta) is a pathological hallmark of Alzheimer's disease (AD).