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283 results for "driving".

Research summaries 260

Showing the best 200 of 260, 71–80, page 8 of 20. Filter these by subject, year and score in the research library →

1. Blood-Based Analysis of Different Tau Variants in Patients With Multiple Traumatic InjuriesResearch summary

   Research summaries · alzhub.org/study/blood-based-analysis-of-different-tau-variants-in-patients-with-41665901

   … biological processes driving tau release. This study measured phosphorylated and nonphosphorylated tau variants in the blood of patients with multiple traumatic injuries to better understand what drives tau release into the …

2. Clinical utility of office-based cognitive predictors of fitness to drive in persons with dementia: A systematic reviewResearch summary

   Research summaries · alzhub.org/study/clinical-utility-of-office-based-cognitive-predictors-of-fitness-to-17198485

   … address this gap are that driving researchers routinely perform cutoff score analyses and that stakeholder organizations (e.g., AMA, American Geriatrics Society) sponsor consensus fora to review driving research methodologies. …

3. Decomposing Urban and Rural Disparities of Preventable ED Visits Among Patients With Alzheimer's Disease and Related Dementias: Evidence of the Availability of Health Care ResourcesResearch summary

   Research summaries · alzhub.org/study/decomposing-urban-and-rural-disparities-of-preventable-ed-visits-32613666

   … shortage area is one of the driving factors (contributing to 27%-48%) that explained the urban and rural disparities. Our study demonstrates the importance of improving health care resources in rural areas to improve health care …

4. Ethical challenges related to capacity, competence and autonomy in individuals with dementiaResearch summary

   Research summaries · alzhub.org/study/ethical-challenges-related-to-capacity-competence-and-autonomy-in-8150892e

   … financial capacity, driving and voting.Secondarily, we aim to discuss a new ethical issue emerging from using artificial intelligence and machine learning to improve autonomy in individuals with dementia.Furthermore, we will …

5. Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell lineResearch summary

   Research summaries · alzhub.org/study/expression-of-the-phagocytosis-essential-protein-trem2-is-down-23778113

   … cores. A major factor driving Aβ42 peptide accumulation is the inability of brain cells to effectively clear excessive amounts of Aβ42 via phagocytosis. The trans-membrane spanning, sensor-receptor known as the "triggering …

6. High frame rate in vivo two-photon microscopy to quantify murine cerebrospinal fluid flow heterogeneityResearch summary

   Research summaries · alzhub.org/study/high-frame-rate-in-vivo-two-photon-microscopy-to-quantify-murine-95944ba3

   … However, the mechanisms driving CSF flow and its oscillatory dynamics remain poorly understood. Using high frame rate two-photon imaging (up to 113 Hz), we show that CSF flow is spatially heterogeneous and highly pulsatile, …

7. Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer's diseaseResearch summary

   Research summaries · alzhub.org/study/innate-immune-sensing-of-z-nucleic-acids-by-zbp1-ripk1-axis-drives-40902587

   … amplified in AD microglia, driving innate immune responses and neuroinflammation through sensing Z-form mitochondrial DNA (mtDNA). We show that oxidized mtDNA, generated by amyloid-β (Aβ)-induced oxidative stress, was fragmented …

8. Interplay between Brain Pericytes and Endothelial Cells in DementiaResearch summary

   Research summaries · alzhub.org/study/interplay-between-brain-pericytes-and-endothelial-cells-in-dementia-34329605

   … crosstalk is a major driving force in dementia pathology. Disruption of the BBB in dementia precipitates cognitive decline. This review highlights how dysfunction of the endothelial-pericyte crosstalk contributes to dementia, …

9. Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS MutationsResearch summary

   Research summaries · alzhub.org/study/loss-of-dynamic-rna-interaction-and-aberrant-phase-separation-induced-31630970

   … role of arginine in driving proper RNA interaction. Glycine mutations undergo rapid loss of fluidity, emphasizing the role of glycine in promoting fluidity. Strikingly, the nuclear import receptor Karyopherin-β2 reverses the …

10. Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health DataResearch summary

    Research summaries · alzhub.org/study/methodology-for-establishing-a-community-wide-life-laboratory-for-30102277

    … wearable actigraphs. Driving sensors are also installed in participants' cars and computer (PC, tablet or smartphone) use is tracked. Data is annotated via frequent online self-report options that provide vital information with …

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