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199 results for "antipsychotic".

Research summaries 180

Showing 141–150, page 15 of 18. Filter these by subject, year and score in the research library →

  1. From revolution to evolution: the glutamate hypothesis of schizophrenia and its implication for treatmentResearch summary

    Research summaries · alzhub.org/study/from-revolution-to-evolution-the-glutamate-hypothesis-of-21956446

    … efficacy as conventional antipsychotic drugs for treating positive and negative symptoms of schizophrenia. In addition, NMDAR has intrinsic modulatory sites that are active targets for drug development, several of which show …

  2. Sundown syndrome in persons with dementia: an updateResearch summary

    Research summaries · alzhub.org/study/sundown-syndrome-in-persons-with-dementia-an-update-22216036

    … receptor antagonists, antipsychotics, and behavioral modifications. To decrease the morbidity from this specific condition, improve patient's well being, lessen caregiver burden, and delay institutionalization, further attention …

  3. Assessment of potentially inappropriate medications using STOPPFrail V2 criteria and OncPal guideline in elderly cancer patients with end-stage disease: A cross-sectional studyResearch summary

    Research summaries · alzhub.org/study/assessment-of-potentially-inappropriate-medications-using-stoppfrail-7bc8dc76

    … lipid-lowering drugs (7.65%), antipsychotics in dementia (7.10%), nutritional supplements (7.10%), and glucose-lowering agents (6.56%). Polypharmacy (≥ 5 drugs) was observed in 85.80% of patients. Under both criteria, the number …

  4. Multiple anticholinergic medication use and risk of hospital admission for confusion or dementiaResearch summary

    Research summaries · alzhub.org/study/multiple-anticholinergic-medication-use-and-risk-of-hospital-25284144

    … excluding individuals taking antipsychotics. Results Adjusted results showed a significantly greater risk of hospitalization for confusion or dementia when individuals were taking two or more anticholinergic medications. The …

  5. Short-Horizon Metrics and the Persistence of Capacity-Debiting Practices in Nursing HomesResearch summary

    Research summaries · alzhub.org/study/short-horizon-metrics-and-the-persistence-of-capacity-debiting-2a1988c1

    Interventions that reduce functional capacity — antipsychotics or benzodiazepines for agitation, activity restriction for fall prevention, prolonged bed rest, incontinence product use, and catheterization — remain common in …

  6. Management of agitation and aggression associated with Alzheimer diseaseResearch summary

    Research summaries · alzhub.org/study/management-of-agitation-and-aggression-associated-with-alzheimer-19488082

    … these symptoms-atypical antipsychotics-have a modest but significant beneficial effect in the short-term treatment (over 6-12 weeks) of aggression but limited benefits in longer term therapy. Benefits are less well established …

  7. New insights: dose-response relationship between psychotropic drugs and falls: a study in nursing home residents with dementiaResearch summary

    Research summaries · alzhub.org/study/new-insights-dose-response-relationship-between-psychotropic-drugs-21628599

    … relationships for the use of antipsychotics (hazard ratio [HR], 2.78; 95% confidence interval [CI], 1.49-5.17), anxiolytics (1.60; 1.20-2.14), hypnotics and sedatives (2.58; 1.42-4.68), and antidepressants (2.84; 1.93-4.16). Fall …

  8. Pain management in patients with dementiaResearch summary

    Research summaries · alzhub.org/study/pain-management-in-patients-with-dementia-24204133

    … inappropriate treatment with antipsychotic medications. Pain also contributes to further complications in treatment and care. This review explores four key perspectives of pain management in dementia and makes recommendations for …

  9. Treatment of psychosis and dementia in Parkinson's diseaseResearch summary

    Research summaries · alzhub.org/study/treatment-of-psychosis-and-dementia-in-parkinson-s-disease-24464490

    … PD are much needed. Antipsychotics with dopamine-blocking properties can worsen parkinsonian motor features and have been associated with increased morbidity and mortality in elderly, dementia patients. For treating PD psychosis, …

  10. Adverse drug reactions in special populations - the elderlyResearch summary

    Research summaries · alzhub.org/study/adverse-drug-reactions-in-special-populations-the-elderly-25619317

    … morbidity and mortality. Antipsychotics increase the risk of stroke by more than three-fold in patients with dementia. Inappropriate prescribing can be reduced by adherence to prescribing guidelines, suitable monitoring and …

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