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315 results for "driving".

Research summaries 292

Showing the best 200 of 292, 41–50, page 5 of 20. Filter these by subject, year and score in the research library →

  1. Obstructive sleep apnea, cognition and Alzheimer's disease: A systematic review integrating three decades of multidisciplinary researchResearch summary

    Research summaries · alzhub.org/study/obstructive-sleep-apnea-cognition-and-alzheimer-s-disease-a-31881487

    … sleep/cognitive-impairment driving these findings. CPAP treatment may be effective in improving cognition in OSA patients with AD. Recent trends demonstrate links between OSA and AD-biomarkers of neurodegeneration across all …

  2. Longitudinal driving performance in early-stage dementia of the Alzheimer typeResearch summary

    Research summaries · alzhub.org/study/longitudinal-driving-performance-in-early-stage-dementia-of-the-14511152

    Objectives To longitudinally assess on-road driving performance in healthy older adults and those with early-stage dementia of the Alzheimer type (DAT). Design A prospective longitudinal study. Setting Large urban medical center …

  3. Neuroinflammation in Alzheimer diseaseResearch summary

    Research summaries · alzhub.org/study/neuroinflammation-in-alzheimer-disease-39653749

    … their interactions are driving forces behind the spread and progression of the disease. The identification of treatment opportunities will require a precise understanding of the cells and mechanisms involved as well as a clear …

  4. Monomeric C-reactive protein--a key molecule driving development of Alzheimer's disease associated with brain ischaemia?Research summary

    Research summaries · alzhub.org/study/monomeric-c-reactive-protein-a-key-molecule-driving-development-of-26335098

    Alzheimer's disease (AD) increases dramatically in patients with ischaemic stroke. Monomeric C-reactive protein (mCRP) appears in the ECM of ischaemic tissue after stroke, associating with microvasculature, neurons and …

  5. The impact of HIV-related neuropsychological dysfunction on driving behavior. The HNRC GroupResearch summary

    Research summaries · alzhub.org/study/the-impact-of-hiv-related-neuropsychological-dysfunction-on-driving-10645701

    … may have on automobile driving, we evaluated 68 HIV-seropositive drivers using an NP battery and two PC-based driving simulations. Thirty-two participants were classified as NP impaired; most (72%) evidenced only mild impairment, …

  6. ApoE in Alzheimer's disease: pathophysiology and therapeutic strategiesResearch summary

    Research summaries · alzhub.org/study/apoe-in-alzheimer-s-disease-pathophysiology-and-therapeutic-strategies-36348357

    … the brain with apoE4 driving earlier and more abundant amyloids. ApoE isoforms also have differential effects on multiple Aβ-related or Aβ-independent pathways. The complexity of apoE biology and pathobiology presents challenges …

  7. Astrocyte contribution to dysfunction, risk and progression in neurodegenerative disordersResearch summary

    Research summaries · alzhub.org/study/astrocyte-contribution-to-dysfunction-risk-and-progression-in-36316501

    … function, and may suggest a driving role for astrocytes in disease initiation, is discussed. A summary of how astrocyte transcriptomic and proteomic signatures are altered during the progression of neurodegenerative disorders …

  8. Driving and Alzheimer's disease: the risk of crashesResearch summary

    Research summaries · alzhub.org/study/driving-and-alzheimer-s-disease-the-risk-of-crashes-8255438

    … become incapable of driving, it is not known whether, under current licensing regulations and self-imposed limitations, patients with AD present a definably increased risk of being involved in crashes, and if so, the relative …

  9. Driving performance in persons with mild senile dementia of the Alzheimer typeResearch summary

    Research summaries · alzhub.org/study/driving-performance-in-persons-with-mild-senile-dementia-of-the-8315186

    … Alzheimer type (SDAT) on driving ability. Design Cross-sectional study with correlation analysis. Setting A university-based Alzheimer's Disease Research Center, which evaluates community-living older adult volunteers, and the …

  10. Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategiesResearch summary

    Research summaries · alzhub.org/study/apolipoprotein-e-and-alzheimer-disease-pathobiology-and-targeting-31367008

    … the risk of AD is by driving earlier and more abundant amyloid pathology in the brains of APOE*ε4 carriers. The number of amyloid-β (Aβ)-dependent and Aβ-independent pathways that are known to be differentially modulated by APOE …

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