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315 results for "driving".

Research summaries 292

Showing the best 200 of 292, 11–20, page 2 of 20. Filter these by subject, year and score in the research library →

  1. White Matter Hyperintensities Predict Driving Behavior Changes in Preclinical Alzheimer’s DiseaseResearch summary

    Research summaries · alzhub.org/study/white-matter-hyperintensities-predict-driving-behavior-changes-in-41433463

    Our study included 74,275 weeks of driving data (2015-2024, average follow-up 6.1 years). Increased WMH burden correlated with decreased trip frequency (p = 0.0005), fewer near-home trips (p = 0.0004), reduced unique destinations …

  2. Mild cognitive impairment, Alzheimer's disease dementia, and predictors of driving cessation: A 7-year longitudinal prospective studyResearch summary

    Research summaries · alzhub.org/study/mild-cognitive-impairment-alzheimer-s-disease-dementia-and-predictors-40261306

    BackgroundPatients with dementia face driving difficulties and, at some point, cease driving.ObjectiveWe sought to identify predictors of driving cessation among patients with mild cognitive impairment (MCI) or mild Alzheimer's …

  3. Driving into diagnosis: Leveraging high-resolution telematics and sensorimotor profiling to identify preclinical Alzheimer's diseaseResearch summary

    Research summaries · alzhub.org/study/driving-into-diagnosis-leveraging-high-resolution-telematics-and-41393339

    … lack generalizability. Driving and sensorimotor performance may reveal prodromal changes. Objective We tested whether features from high-frequency driving trips detect preclinical AD and whether demographic, genetic, or …

  4. Microglia-Derived Extracellular Vesicles from Alzheimer’s Disease Patients Carry miRNAs Driving a Neuroinflammatory ResponseResearch summary

    Research summaries · alzhub.org/study/microglia-derived-extracellular-vesicles-from-alzheimers-disease-41678018

    … these cells, thereby driving a neuroinflammatory response. Taken together, putatively microglia-derived EVs from the CSF of AD patients contain miRNAs, which are capable of activating hTLR8 and inducing an inflammatory response …

  5. Everyday Driving and Plasma Biomarkers in Alzheimer's Disease: Leveraging Artificial Intelligence to Expand Our Diagnostic ToolkitResearch summary

    Research summaries · alzhub.org/study/everyday-driving-and-plasma-biomarkers-in-alzheimer-s-disease-36938737

    Background Driving behavior as a digital marker and recent developments in blood-based biomarkers show promise as a widespread solution for the early identification of Alzheimer's disease (AD). Objective This study used …

  6. Implementation and evaluation of a driving cessation intervention to improve community mobility and wellbeing outcomes for people living with dementia: study protocol of the 'CarFreeMe' for people with dementia programResearch summary

    Research summaries · alzhub.org/study/implementation-and-evaluation-of-a-driving-cessation-intervention-to-30832581

    … change their approach to driving. The driving cessation intervention may fill an important gap in service delivery to people living with dementia who are adjusting to life without driving. Trial registration Australian and New …

  7. Cognitive and brain reserve predict decline in adverse driving behaviors among cognitively normal older adultsResearch summary

    Research summaries · alzhub.org/study/cognitive-and-brain-reserve-predict-decline-in-adverse-driving-36619039

    Daily driving is a multi-faceted, real-world, behavioral measure of cognitive functioning requiring multiple cognitive domains working synergistically to complete this instrumental activity of daily living. As the global …

  8. Systematic review of driving risk and the efficacy of compensatory strategies in persons with dementiaResearch summary

    Research summaries · alzhub.org/study/systematic-review-of-driving-risk-and-the-efficacy-of-compensatory-17537088

    … dementia are at greater driving risk and, if so, to estimate the magnitude of this risk and determine whether there are efficacious methods to compensate for or accommodate it. Design Systematic review of the literature. Setting …

  9. Improving quality of life for institutionalized individuals with advanced dementia: A pilot study on efficacy of a semi-immersive virtual reality driving simulator for individuals with advanced dementiaResearch summary

    Research summaries · alzhub.org/study/improving-quality-of-life-for-institutionalized-individuals-with-940f3080

    • A novel semi-immersive VR driving simulator (VRDS) for institutionalized older adults with advanced dementia. • The VRDS integrates realistic driving with a virtual environment to stimulate implicit memory and improve cognitive …

  10. The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation ScienceResearch summary

    Research summaries · alzhub.org/study/the-multi-partner-consortium-to-expand-dementia-research-in-latin-33776890

    … and economic factors driving the presentation of frontotemporal dementia and Alzheimer's disease in Latin America relative to the US. We describe ongoing ReDLat studies in various fields and ongoing research extensions. Then, we …

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