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315 results for "driving".

Research summaries 292

Showing the best 200 of 292, 181–190, page 19 of 20. Filter these by subject, year and score in the research library →

1. Frontal white matter lesions in Alzheimer's disease are associated with both small vessel disease and AD-associated cortical pathologyResearch summary

   Research summaries · alzhub.org/study/frontal-white-matter-lesions-in-alzheimer-s-disease-are-associated-34608542

   … degenerative mechanism driving posterior white matter disruption, and both AD-associated degenerative and vascular mechanisms contributed to anterior matter disruption. In this pilot study, we used human post-mortem brain tissue …

2. Light-Induced Pupillary Responses in Alzheimer's DiseaseResearch summary

   Research summaries · alzhub.org/study/light-induced-pupillary-responses-in-alzheimer-s-disease-31031692

   … The main hypothesis driving pupillometry research in AD is based on the concept that the AD-related neurodegeneration affects both the parasympathetic and the sympathetic arms of the PLR (cholinergic and noradrenergic theory), …

3. Loss of Dynamic RNA Interaction and Aberrant Phase Separation Induced by Two Distinct Types of ALS/FTD-Linked FUS MutationsResearch summary

   Research summaries · alzhub.org/study/loss-of-dynamic-rna-interaction-and-aberrant-phase-separation-induced-31630970

   … role of arginine in driving proper RNA interaction. Glycine mutations undergo rapid loss of fluidity, emphasizing the role of glycine in promoting fluidity. Strikingly, the nuclear import receptor Karyopherin-β2 reverses the …

4. Microbiome-generated amyloid and potential impact on amyloidogenesis in Alzheimer's disease (AD)Research summary

   Research summaries · alzhub.org/study/microbiome-generated-amyloid-and-potential-impact-on-amyloidogenesis-26097896

   … the primary influence driving Alzheimer's disease (AD) pathogenesis, and Aβ peptide accretion is the result of an imbalance between Aβ peptide production and clearance. In the last 18 months multiple laboratories have reported …

5. Multi-label, multi-domain learning identifies compounding effects of HIV and cognitive impairmentResearch summary

   Research summaries · alzhub.org/study/multi-label-multi-domain-learning-identifies-compounding-effects-of-34706304

   … Finally, brain patterns driving the subject-level predictions across all four cohorts characterize the independent and compounding effects of HIV and CI in the HAND cohort. Based on cross-validation on the UCSF dataset, the …

6. Targeting HIV-Related Neurocognitive Impairments with Cognitive Training Strategies: Insights from the Cognitive Aging LiteratureResearch summary

   Research summaries · alzhub.org/study/targeting-hiv-related-neurocognitive-impairments-with-cognitive-30710223

   … adherence, employment, and driving ability, thus reducing quality of life. As the number of older adults with HIV continues to grow, many will become vulnerable to cognitive frailty, especially as they experience …

7. Tumor necrosis factor-α synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's diseaseResearch summary

   Research summaries · alzhub.org/study/tumor-necrosis-factor-synthesis-inhibitor-3-6-dithiothalidomide-22642825

   … neuroinflammation is the driving force behind these disorders, compelling evidence implicates its role in exacerbating disease progression, with a key player being the potent proinflammatory cytokine TNF-α. Elevated TNF-α levels …

8. Be a Super Shopper!Research summary

   Research summaries · alzhub.org/study/be-a-super-shopper-ff072978

   … as powerful mechanism driving precautionary consumption. While Whole Foods Market is not the only market actor encouraging precautionary consumption, the company has helped to mark the grocery store as a site where a new, much …

9. Expression of the phagocytosis-essential protein TREM2 is down-regulated by an aluminum-induced miRNA-34a in a murine microglial cell lineResearch summary

   Research summaries · alzhub.org/study/expression-of-the-phagocytosis-essential-protein-trem2-is-down-23778113

   … cores. A major factor driving Aβ42 peptide accumulation is the inability of brain cells to effectively clear excessive amounts of Aβ42 via phagocytosis. The trans-membrane spanning, sensor-receptor known as the "triggering …

10. Interplay among gut microbiota, intestinal mucosal barrier and enteric neuro-immune system: a common path to neurodegenerative diseases?Research summary

    Research summaries · alzhub.org/study/interplay-among-gut-microbiota-intestinal-mucosal-barrier-and-enteric-29797112

    … represent a common path driving the onset of the main neurodegenerative diseases, even though each disease displays its own distinct clinical features. Neurological diseases, such as Parkinson's disease, Alzheimer's disease, …

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