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315 results for "driving".

Research summaries 292

Showing the best 200 of 292, 111–120, page 12 of 20. Filter these by subject, year and score in the research library →

1. Vascular Considerations for Amyloid ImmunotherapyResearch summary

   Research summaries · alzhub.org/study/vascular-considerations-for-amyloid-immunotherapy-36269539

   … 2000s, and the mechanisms driving it are still unknown. Recent approval of aducanumab comes with renewed urgency to consider vascular deficits caused by anti-Aβ immunotherapy. This article reviews the history of anti-Aβ …

2. Cognitive Intra-individual Variability in HIV: an Integrative ReviewResearch summary

   Research summaries · alzhub.org/study/cognitive-intra-individual-variability-in-hiv-an-integrative-review-34826006

   … everyday functioning (i.e., driving simulation performance), specifically medication adherence, and 4) even mortality. This inspires future directions for research. First, greater cognitive intraindividual variability may reflect …

3. Cognitive impairment in the U.S.: Lifetime risk, age at onset, and years impairedResearch summary

   Research summaries · alzhub.org/study/cognitive-impairment-in-the-u-s-lifetime-risk-age-at-onset-and-years-32300635

   … identify the mechanisms driving these disparities in cognitive impairment. This analysis estimated that about two out of three Americans age 50 and older experience some cognitive impairment, with lifetime dementia risk of 37% …

4. Decomposing Urban and Rural Disparities of Preventable ED Visits Among Patients With Alzheimer's Disease and Related Dementias: Evidence of the Availability of Health Care ResourcesResearch summary

   Research summaries · alzhub.org/study/decomposing-urban-and-rural-disparities-of-preventable-ed-visits-32613666

   … shortage area is one of the driving factors (contributing to 27%-48%) that explained the urban and rural disparities. Our study demonstrates the importance of improving health care resources in rural areas to improve health care …

5. Ethical challenges related to capacity, competence and autonomy in individuals with dementiaResearch summary

   Research summaries · alzhub.org/study/ethical-challenges-related-to-capacity-competence-and-autonomy-in-8150892e

   … financial capacity, driving and voting.Secondarily, we aim to discuss a new ethical issue emerging from using artificial intelligence and machine learning to improve autonomy in individuals with dementia.Furthermore, we will …

6. Hypoglycaemia in diabetes mellitus: epidemiology and clinical implicationsResearch summary

   Research summaries · alzhub.org/study/hypoglycaemia-in-diabetes-mellitus-epidemiology-and-clinical-25287289

   … everyday activities such as driving, work performance and leisure pursuits. In addition to accidents and physical injury, the morbidity of hypoglycaemia involves the cardiovascular and central nervous systems. Whereas coma and …

7. Ibuprofen modulates inflammatory and autophagy-associated pathways linked to neurodegenerative pathology in APOE-context-dependent cellular modelsResearch summary

   Research summaries · alzhub.org/study/ibuprofen-modulates-inflammatory-and-autophagy-associated-pathways-e38b6498

   … solely dependent on the driving power of the immune cytokine interleukin-1 beta (IL-1β), arising from neuronal distress and release of sAPPα, which activates microglia for synthesis and release of IL-1β driving synthesis of βAPP, …

8. Neurobiology of dementiaResearch summary

   Research summaries · alzhub.org/study/neurobiology-of-dementia-86818921

   … these processes are driving the development of biomarkers and disease-modifying therapies, paving the way for more precise, personalized approaches to diagnosis and care. This chapter describes dementia as a multifactorial …

9. Next-generation neurotherapeutics: mechanistic insights on monoclonal antibodies in Alzheimer's diseaseResearch summary

   Research summaries · alzhub.org/study/next-generation-neurotherapeutics-mechanistic-insights-on-monoclonal-41241266

   … synergistic effectiveness, driving next-generation engineering advances including Fc modifications that reduce ARIA risk, nanobodies/single-chain variable fragments (scFvs) with enhanced blood-brain barrier (BBB) penetration, …

10. Oxidative Stress as a Central Mechanistic Bridge Between Alzheimer’s and Vascular Pathologies in Mixed Dementia: Emerging Evidence and Therapeutic PerspectivesResearch summary

    Research summaries · alzhub.org/study/oxidative-stress-as-a-central-mechanistic-bridge-between-alzheimers-41595595

    … molecular mechanism driving both neurodegenerative and vascular pathologies in MD. Reactive oxygen species (ROS) contribute to amyloid-β aggregation, tau hyperphosphorylation, endothelial dysfunction, and blood-brain barrier …

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